白血病女孩被艾滋病毒奇迹治愈〔英语〕.docx
白血病女孩被艾滋病毒奇迹治愈英语白血病女孩被艾滋病毒奇迹治愈英语下面是学习啦我整理的白血病女孩被艾滋病毒奇迹治愈,希望对大家有帮助。ThecancergirlcuredbytheHIVvirus:Seven-year-oldmakesextraordinaryrecoveryafterU.S.doctorsre-wireherimmunesystemtodestroyleukaemiacellsInAprilthisyear,EmilyWhiteheadsfamilyhadalmostgivenuphope.Thebravesix-year-oldhadbeenfightingleukaemiafortwoyears,onlytorelapseforasecondtimeduringintensivechemotherapytreatmentinFebruary.DoctorshadexhaustedallthetraditionaltreatmentsasEmilycouldnotremaininremissionforlongenoughtoattemptabonemarrowtransplant.Soherdesperateparents,KariandTom,startedlookingatmoreradicaloptions.Fightingfit:Emily(seenleftduringtreatmentinApril)hasnowbeeninremissionfromcancerforsevenmonthsWemadethedecisionthatweneededtogosomewhereelse,saidMrsWhitehead.Weneededtotrysomethingnew,differentandcutting-edge.SotheyturnedtotheCancerCenteratTheChildrensHospitalofPhiladelphia,whichisinvolvedintestingapioneeringnewtherapy.DoctorssuggestedtheysignEmilyuptoaclinicaltrialthatwoulduseadisabledformofHIVtocarrycancer-fightinggenesintoherT-cells(diseasefightingcells).Thehopewasthatthiswouldre-programmeherimmunesystemtorecognisethecancercellsandstartkillingthem.SeveraladultshadalreadybeenenrolledinthestudyattheHospitaloftheUniversityofPennsylvaniaandhadrespondedwell,butasitwassonewthetreatmentwasntwithoutrisks.ButtimewasrunningoutforEmily,whoisalsoknownasEmma.MrWhiteheadsaid:Weweretoldthatweweredownto48hoursofmakingadecisionorshecouldstarthavingorganfailure.Theycomfortedthemselveswiththeknowledgethatevenifthetreatmentdidntwork,itwouldprovidedoctorswithinformationthatcouldhelpthemsaveothersickchildren.SoonApril17,thethensix-year-oldbecamethefirstchildtohavethetherapyknownasCTL019.Emilyduringhertherapy-atfirstshesufferedanadversereaction,whichwastreatedwithanarthritisdrugNowinremission,EmilyenjoyswalkingherdogwhocomfortedherwhenshewasillThefamilyhadbeenwarnedEmilycouldexperienceflu-likesymptomsafewdaysafterherre-engineeredT-cellswereinjectedbackintoher.Buthersymptomswerefarmoreseriousthandoctorsanticipated.Shebecamecriticallyillandwasadmittedtointensivecareatthechildrenshospital.OnApril24,doctorstoldherparentsshehadaonein1,000chanceofsurvivingthenight.TrialleaderDrStephanGruppandhisteamrealisedthatthelevelofacertainproteinhadbecomeveryelevatedasaresultoftheT-cellsgrowinginEmilysbody.Thissameproteinisinvolvedinrheumatoidarthritis,andthereisadrugforthatdiseasethatturnsoffproductionofthatparticularprotein.TheteamadministeredthedrugtoEmily,withdramaticresults.Almostovernight,herbreathingimproved,herfeverdroppedandherbloodpressurewasbacktonormal.MrsWhiteheadsaidEmilyinspiredthemwithhowshecoped.Shesextremelysmartandcreative.Shesfunny-shemakesuslaughallthetime.Shenevercomplains,shesaid.KiraandTomfacedtheagonisingdecisionofwhetherornottoputtheirdaughterforwardforaclinicaltrialHerhusbandadded:Shetoldusfromthebeginningthatshewouldcontinuetofightanddowhatweaskedaslongasweweretherewithher.Wevestucktogetherasateam.Shesdefinitelyourhero.SeveralweeksafterherT-cellinfusion,theywereabletoconductabonemarrowtesttofindoutifthetherapyhadworked.Threeweeksafterreceivingthetreatment,shewasinremission,saidDrGrupp.EmilycompletelyrespondedtoherT-celltherapy.Wecheckedherbonemarrowforthepossibilityofdiseaseagainatthreemonthsandsixmonthsoutfromhertreatment,andshestillhasnodiseasewhatsoever.Thecancer-fightingT-cellsarestillthereinherbody.Headdedthattheyneedtoseetheremissiongoonforacoupleofyearsbeforetheycanthinkaboutwhethersheiscuredornot.But,afterspendingyearsintreatment,EmilywenthomeinJuneandnowenjoysgoingtoschool,playingfootballandwalkingherdogLucy.T-celltherapywasreallytheonlyoptionleftforEmily,saidMrWhitehead.Butweenteredherintothetrialreallyhopeful,andfromtheverybeginningwejustreallyhadagoodfeelingaboutit.Soallalongwesaid,itjusthastowork,ithastoworkforEmilyanditdid.Thescientistssaidalthoughtheresultswereverypromising,muchmoreresearchneedstobedonetoseewhetherthetherapyisaviable,safeandlong-termsolutionforcontrollingcertaincancersinchildrenandadultsKenCampbell,ClinicalInformationOfficeratLeukaemiaLymphomaResearch,saidtheresultsofthestudywereencouragingforbothchildrenandadultsdiagnosedwithleukaemia.Treatmentswhichmodifythebodysownimmunesystemtofightleukaemiahaveshownmuchpromiseinrecentyears,hesaid.Whatissignificantaboutthetherapyisthatthesevereside-effectsassociatedwiththisformoftreatmentseemtobegreatlyreducedwhencombinedwithotherdrugs.Thisisasmallstudyofjust12patients.LargerclinicaltrialsareneededtodeterminehoweffectivethistreatmentcouldbeandasaresultitshouldbesometimebeforeitisavailableintheUK.ResearchersfromtheUniversityofPennsylvaniaandChildrensHospitalofPhiladelphiapresentedtheirlatestfindingsattheAmericanSocietyofHematologysannualmeetinginAtlanta.Theyfoundnineoutof12patientsinthetrial,whichincludedEmilyandoneotherchild,respondedtothetreatment.Theirgoalistotreatanother12patientsoverthenextyear.白血病女孩被艾滋病毒奇迹治愈英语ThecancergirlcuredbytheHIVvirus:Seven-year-oldmakesextraordinaryrecoveryafterU.S.doctorsre-wireherimmunesystemtodestroyleukaemiacellsInAprilthisyear,EmilyWhiteheadsfamilyhadalmostgivenup推荐度: