中国专利数据库上课讲义.doc

Good is good, but better carries it.精益求精，善益求善。中国专利数据库-中国专利数据库(CNIP)检索条件：（摘要=纤维素and摘要=医用材料)(精确匹配)检索结果：551滕锡山,冯博智.用纤维素材料制备可溶性防粘连材料的方法及其产品P.辽宁：CN1269376,2000-10-11.2张秀成,李红媛.纤维素、微晶纤维素、聚碳酸亚丙酯组合物及其制备方法P.黑龙江：CN103571166A,2014-02-12.3何春菊,马博谋.一种以二元溶剂体系制备壳聚糖纤维素复合纤维的方法P.上海：CN102828283A,2012-12-19.4尹娜,陈仕艳,欧阳炀,徐秋舒,汤廉,颜志勇,王华平.一种细菌纤维素/藕粉复合材料及其生物制备方法P.上海：CN103571899A,2014-02-12.5郑裕东,吴健,高爽,丁寻,崔秋艳,余弈,刘向阳,何欣扬.一种胶原修饰细菌纤维素复合膜的制备方法P.北京：CN102352051A,2012-02-15.6万怡灶,张晶,罗红林,朱勇,王哲人.细菌纤维素/卵磷脂复合材料及制备和应用P.天津：CN103467778A,2013-12-25.7郑裕东,史湘宁,张泽钰,张威,彭韵凌,林清华.一种刺激响应型酯化纳米纤维素前药缓释材料的制备方法P.北京：CN103191441A,2013-07-10.8位晓娟,顾其胜,奚廷斐,王庆生.一种交联海藻酸-细菌纤维素海绵及其制备方法P.山东：CN103536954A,2014-01-29.9曹献英,陈胜杰,操凤,郑育声,杜杰,陈欢.壳寡糖/细菌纤维素海绵的制备方法P.海南：CN103007335A,2013-04-03.10郑裕东,崔秋艳,吴健,彭帅,栾家斌.一种氧化纳米细菌纤维素的制备方法P.北京：CN102604142A,2012-07-25.11余厚咏,姚菊明,董延娟.一种纤维素纳米晶表面酯化的改性方法P.浙江：CN103382225A,2013-11-06.12郑裕东,崔秋艳,吴健,高爽,栾家斌,刘国权.一种多聚糖与纳米细菌纤维素的复合伤口敷料的制备方法P.北京：CN102727926A,2012-10-17.13尹娜,李喆,王华平,陈仕艳,洪枫,欧阳炀,杨敬轩,徐秋舒.一种细菌纤维素支架材料的制备方法及其制品P.上海：CN102274549A,2011-12-14.14秦宗益,刘彦男,梁浜雷,程淼,唐诗杰.一种羧基化纤维素纳米球的制备方法P.上海：CN102911273A,2013-02-06.15钟春燕,钟宇光.含植物成分的细菌纤维素复合羊膜细胞外基质敷料制备方法P.海南：CN103893816A,2014-07-02.16屠美,查振刚,曾戎,吴昊,韩婉清.一种生物功能化羟丙基纤维素酯类液晶膜的制备及其应用P.广东：CN103739866A,2014-04-23.17邓红兵,王先恺,詹颖菲,忻尚璟,杜予民,施晓文.一种基于溶菌酶和丝蛋白的层层自组装改性纤维素纳米纤维膜及其制备与应用P.湖北：CN103536958A,2014-01-29.18马兆成,闫会清,季群,彭抒昂,邓秀新.一种果胶/纤维素水凝胶材料及其制备方法P.湖北：CN102585255A,2012-07-18.19曹献英,杜晶晶,林强,冯玉红,王锡彬,吴周新,牛成,庞素娟,尹学琼,朱清梅,吴敏,徐田军,鲁战平,胡凌俊.一种羧甲基纤维素和细菌纤维素复合材料的制备方法P.海南：CN101530749,2009-09-16.20穆畅道,林炜,李宏利,彭洲.双醛羧甲基纤维素的制备及其醛基含量的检测方法P.四川：CN101250827,2008-08-27.21郑裕东,林清华,王红,樊卫,安家新.改性纳米纤维素多孔复合型高吸渗止血敷料的制备方法P.北京：CN102961777A,2013-03-13.22朱新生,张伟,刘颖,李青松,周正华,刘兆峰,俞波.一种增强羟丙基纤维素微孔膜及其制备方法P.江苏：CN103059334A,2013-04-24.23张俐娜,汤虎,常春雨.一种纤维素/甲壳素共混膜的制备方法P.湖北：CN101864089A,2010-10-20.24王华平,杨敬轩,李喆,吴旭君,孙晓晓,陈仕艳.一种具有梯度结构的细菌纤维素膜及其制备方法P.上海：CN103233050A,2013-08-07.25邓红兵,杜予民,施晓文,张俐娜.固定溶菌酶-累托石的纳米纤维复合膜的制备方法P.湖北：CN103300071A,2013-09-18.26张雯,王华平,陈仕艳,周碧辉,张泽锐,李哲,张万灵.一种防病毒型细菌纤维素防护材料的制备方法及其制品P.上海：CN102321261A,2012-01-18.27田浩,罗章凯,王翔,杨力,张文.一种血液灌流用多孔纤维素微球吸附剂及其制备方法P.重庆：CN102794161A,2012-11-28.28刘鹏清,姜猛进,徐建军,叶光斗,王建铨,李昭,晏明,彭华金,游彦,刘晓惠.一种以多元羧酸交联醋酸纤维素纤维的制备方法P.四川：CN103060939A,2013-04-24.29卿彦,吴义强.一种强酸预处理辅助制备纤维素纳米纤丝的方法P.湖南：CN103061174A,2013-04-24.30杜道林,孙见凡,薛永来.醋酸纤维素膜表面交联壳聚糖亲水性膜的制备方法P.江苏：CN102653597A,2012-09-05.31万同,朱勇.一种细菌纤维素/聚乙烯醇复合凝胶材料及其制备方法P.天津：CN101570616,2009-11-04.32梁伯润,马敬红,孙宾,王庆瑞.医用可吸收氧化再生纤维素止血材料的制备方法P.上海：CN1338475,2002-03-06.33杜予民,汤玉峰,李艳.一种可注射型温敏性壳聚糖/甲基纤维素凝胶及其制备方法P.湖北：CN101066457,2007-11-07.34李素哲,王新光,高明,李鹏达,张志宝,程志,李璟,刘媞,刘俊英.一种医用可吸收氧化纤维素材料及其制备方法P.河北：CN103951757A,2014-07-30.35张连仲,王淑琴,冯博智.羧甲基壳聚糖/羧甲基纤维素防手术粘连膜及其制备方法P.辽宁：CN1481907,2004-03-17.36郑裕东,乔堃,谭珏,彭江,张式博.纳米纤维增强水凝胶仿生人工半月板复合材料的制备方法P.北京：CN102671236A,2012-09-19.37刘鹏清,姜猛进,徐建军,叶光斗,王建铨,李昭,晏明,彭华金,游彦,刘晓惠.一种以高沸点酰胺为溶剂制备交联醋酸纤维素纤维的方法P.四川：CN103014893A,2013-04-03.38陈云,张俐娜,罗丽花,王小梅.纤维素/大豆蛋白质复合海绵及其制备方法P.湖北：CN101143941,2008-03-19.39张海悦.细菌纤维素膜创可贴P.吉林：CN202005908U,2011-10-12.40林莹,朱德权,昝佳,蒋国强,丁富新.一种反向温敏型注射式可植入药物载体材料P.北京：CN1698902,2005-11-23.41史珺,罗志有,罗红军,张香连.一种环糊精超分子复合相变储能超细纤维及其制备方法与应用P.广东：CN103205824A,2013-07-17.42张巍.一种共混功能性手术冲洗液的制备方法P.黑龙江：CN103203014A,2013-07-17.43李洪波.一种多孔止血粉及其制备方法P.山东：CN103381189A,2013-11-06.44王昕.一种新型膏药贴P.天津：CN203417344U,2014-02-05.45李洪波.一种血管支架上抗凝血涂层的制备方法P.贵州：CN103157144A,2013-06-19.46程祥荣,陈凤英.一种义齿粘附剂P.湖北：CN102068388A,2011-05-25.47笪利,王风华,吕园园.一种医用生物多糖止血愈合海绵及其制备方法P.江苏：CN103480033A,2014-01-01.48王新光,高明,李素哲,李鹏达,刘媞,李璟,刘俊英.一种水溶性止血材料及其制备方法P.河北：CN103920181A,2014-07-16.49李洪波.一种可吸收复合人工骨P.贵州：CN103127556A,2013-06-05.50黄斌,陈叶廷,施婷婷.一步法改进生物医用材料表面生物相容性的涂层液及涂层法P.江苏：CN102757723A,2012-10-31.51张津育,钟海英,侯燕民,林国宝.一种医用止血防粘连材料及冲洗液的制备方法P.北京：CN101961505A,2011-02-02.52陈高祥,范纯泉,叶晓健,金彩虹,何丹农.聚磷酸钙-磷酸三钙骨支架的制备方法P.上海：CN101716369A,2010-06-02.53张博.吸收性防粘连材料及其制备方法P.山东：CN102058908A,2011-05-18.54张博.一种基于天然纤维的可溶可吸收性医疗产品及其制备方法P.山东：CN101543639,2009-09-30.55张博.一种可吸收、防粘连止血粉产品及其制备方法P.山东：CN101543640,2009-09-30.其中相关性最大的5篇为1.陈云,张俐娜,罗丽花,王小梅.纤维素/大豆蛋白质复合海绵及其制备方法:湖北,CN101143941P.2008-03-19摘要:本发明公开了一种以纤维素、大豆蛋白质为主要原料的复合海绵及其制备方法。它是将纤维素和大豆蛋白质溶解在氢氧化钠/尿素水溶液中,然后经冷冻、真空干燥法制备复合海绵。通过改变纤维素与大豆蛋白质的比例,通过戊二醛、环氧氯丙烷交联改性,可获得具有不同微观结构和性能的复合材料。动物体内植入实验和体外细胞培养实验表明,这类复合材料具有良好的生物相容性。该方法简单适用,原材料来源广泛,可望制备出具有应用前景的来自天然高分子的可降解生物医用材料。2.梁伯润,马敬红,孙宾,王庆瑞.医用可吸收氧化再生纤维素止血材料的制备方法:上海,CN1338475P.2002-03-06摘要:本发明属医用材料技术领域。具体涉及一种医用可吸氧化再生纤维素止血材料的制备方法。本发明的方法是以再生纤维素为原料,用氧化体系在一定的工艺条件下氧化后,得到的产物再经酸处理,离子化稳定处理,制得医用可吸收氧化再生纤维素止血材料。用本发明方法制得的材料具有良好的止血和吸收能力,在医学临床上有广泛应用价值。3.林莹,朱德权,昝佳,蒋国强,丁富新.一种反向温敏型注射式可植入药物载体材料:北京,CN1698902P.2005-11-23摘要:本发明公开了属于医用材料领域的一种反向温度敏型可注射式植入药物载体材料。由纤维素类衍生物、聚乙二醇、多聚糖和对纤维素类衍生物有盐析作用的盐按凝胶材料组分的重量/体积比组成。本发明通过向“纤维素类衍生物聚乙二醇盐”体系中加入一定浓度多聚糖,增强了体系高分子间的疏水相互作用,加快了体系的胶凝速度,提高了凝胶强度,降低了水化和溶胀程度,提高了凝胶的稳定性,减慢了药物的释放速率。本材料的溶胶溶液在室温下可注射,具有良好的生物相容性和生物降解性,避免了手术植入和取出制剂,可作为皮下埋植、生物组织修复骨架、阴道、眼部、脑外伤治疗、神.4.张博.一种基于天然纤维的可溶可吸收性医疗产品及其制备方法:山东,CN101543639P.2009-09-30摘要:本发明属医用材料技术领域。具体涉及一种基于天然纤维的医用可溶可吸收性止血材料及其制备方法。本发明的方法是以天然纤维为原料,在一定的工艺条件下加工为可溶可吸收性材料后,再与磷酸氢二钠、磷酸氢钠、司盘-80、卡波姆、羧甲基纤维素钠等进行动态化学结合,制得的医用可溶可吸收性止血材料。用本发明方法制得的材料具有良好的防止术后粘连、止血和可吸收能力,5.张博.一种可吸收、防粘连止血粉产品及其制备方法:山东,CN101543640P.2009-09-30摘要:本发明属医用材料技术领域。具体涉及一种止血、防止术后粘连、可安全用于体内的止血粉及其加工方法。本发明由下述重量百分比的物质构成0.1-5的磷酸氢二钠、0.1-8的磷酸氢钠、0.1-10吐温-80、0.1-12二甲基硅油、0.2-25羧甲基纤维素钠,其余为活化后的脱脂棉纤维。本品除具备立刻止血、促进伤口愈合、对伤口极好的吸附性外,还具备独特的防止术后粘连的功能。该功能对于减少患者痛苦,提高患者生存质量具有重要意义。在医学临床上有广泛应用价值。欧洲专利局网站检索条件：CelluloseANDbiomaterial（allofthesewords）检索结果：61.T0151/95(Microspheres/BIOMATERIALSUNIVERSE,INC.)of18.6.1998Location· 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RecentdecisionsBoAbibliographicfileEuropeanCaseLawIdentifier:ECLI:EP:BA:1998:T015195.19980618Dateofdecision:18June1998Casenumber:T0151/95Applicationnumber:89103091.8IPCclass:A61K9/16Titleofapplication:PolylacticacidtypemicrospherescontainingphysiologicallyactivesubstanceandprocessforpreparingthesameApplicantname:BiomaterialsUniverse,Inc.Opponentname:BoehringerMannheimGmbHHoechstAGBoard:3.3.022.T0006/02()of3.2.2005EuropeanCaseLawIdentifier:ECLI:EP:BA:2005:T000602.20050203Dateofdecision:03February2005Casenumber:T0006/02Applicationnumber:96103843.7IPCclass:D01F2/28Titleofapplication:PhotodegradablecelluloseestertowApplicantname:CelaneseAcetate,LLC.Opponentname:RhodiaAcetowGmbHBoard:3.3.073.T1831/07(Wounddressing/ADVANCEDMEDICALSOLUTIONSLTD.)of8.12.2009EuropeanCaseLawIdentifier:ECLI:EP:BA:2009:T183107.20091208Dateofdecision:08December2009Casenumber:T1831/07Applicationnumber:95934759.2IPCclass:A61L15/28Titleofapplication:WounddressingApplicantname:AdvancedMedicalSolutionsLimitedOpponentname:ColoplastA/SJohnson&JohnsonMedicalLtd.Board:3.3.104.T0413/10()of29.11.2012EuropeanCaseLawIdentifier:ECLI:EP:BA:2012:T041310.20121129Dateofdecision:29November2012Casenumber:T0413/10Applicationnumber:03028205.7IPCclass:A61K8/37A61K8/42A61K8/46A61K8/73A61K8/891A61K8/895A61Q5/02A61Q5/12Titleofapplication:AqueoushaircleansingcompositionApplicantname:KAOCORPORATIONOpponentname:BASFPersonalCareandNutritionGmbHUNILEVERPLC/UNILEVERNVBoard:3.3.075.T0365/09()of14.4.2010EuropeanCaseLawIdentifier:ECLI:EP:BA:2010:T036509.20100414Dateofdecision:14April2010Casenumber:T0365/09Applicationnumber:99968778.3IPCclass:C08B37/08Languageofproceedings:ENDownloadandmoreinformation:DecisiontextinEN(PDF,138.975K)DocumentationoftheappealprocedurecanbefoundintheRegisterBibliographicinformationisavailablein:ENVersions:UnpublishedTitleofapplication:Cross-linkedhyaluronicacidsandmedicalusesthereofApplicantname:SigmarItaliaS.p.A.Opponentname:FidiaFarmaceuticiS.P.A.Board:3.3.036.T0785/05()of18.12.2007EuropeanCaseLawIdentifier:ECLI:EP:BA:2007:T078505.20071218Dateofdecision:18December2007Casenumber:T0785/05Applicationnumber:99968778.3IPCclass:C08B37/08Titleofapplication:Cross-linkedhyaluronicacidsandmedicalusesthereofApplicantname:SigmarItaliaS.p.A.Opponentname:FidiaFarmaceuticiS.P.A.Board:3.3.03美国专利检索系统检索专利文献检索条件：CelluloseANDbiomaterial检索结果：2233其中一百篇PAT.NO.Title18,889,828Conformationsofdivergentpeptideswithmineralbindingaffinity28,889,776Highdielectricconstantcompositematerialsandmethodsofmanufacture38,889,745Fibrouscalciumpyrophosphateparticlesandmethodsofmakingandusingsame48,889,615Methodsforpromotingepithelializationandhealingofchronicwounds58,889,165Injectablecalcium-phosphatecementreleasingaboneresorptioninhibitor68,888,675Apparatusandmethodsforsupportingcardiacischemictissue78,886,334Systems,methods,anddevicesusingstretchableorflexibleelectronicsformedicalapplications88,886,272Analytesensor98,883,964Compositionscomprisingmodifiedcollagenandusestherefor108,883,915Hydrophobicandhydrophilicinterpenetratingpolymernetworksderivedfromhydrophobicpolymersandmethodsofpreparingthesame118,883,803InhibitorsofBruton'styrosinekinaseforthetreatmentofsolidtumors128,883,435InhibitorsofBruton'styrosinekinase138,883,184Methodsandcompositionsforregeneratingconnectivetissue148,883,182Methodandmaterialforenhancedtissue-biomaterialintegration158,882,847Patientselectablekneejointarthroplastydevices168,881,365Implantablegraftdevicehavingtreatedyarnandmethodformakingsame178,880,137Analytemonitoringdeviceandmethodsofuse188,877,705Biomaterialforthecontrolleddeliveryofingredients198,877,498Porouspolymerscaffoldsforneuraltissueengineeringandmethodsofproducingthesame208,877,469Methodofdryingbiologicalmaterial218,877,224Compositionsforpreventingcardiacarrhythmia228,877,195Monoclonalantibodiestofibrin238,877,180Humanplacentalcollagencompositions,andmethodsofmakingandusingthesame248,877,172Zwitterionicpolymerbioconjugatesandrelatedmethods258,877,012Pipingsystemfromreactortoseparatorandmethodtocontrolprocessflow268,874,204Implantablemedicaldevicescomprisingisolatedextracellularmatrix278,871,709Syntheticchimericproteinscomprisingepidermalgrowthfactorandvitronectin288,871,248Compositionsfortreatingbiofilmsandmethodsforusingsame298,870,954Platelet-derivedgrowthfactorcompositionsandmethodsforthetreatmentoftendonandligamentinjuries308,870,914Medicaldeviceandamethodforsealingapunctureoranopening318,865,964Biomaterials,theirpreparationbyelectrospinningandtheiruseinthebiomedicalandsurgicalfield328,865,879Chitosanbeadsandfillercomprisingsuchbeads338,865,658Compositionscontaining,methodsinvolving,andusesofnon-naturalaminoacidsandpolypeptides348,864,843Biomimmeticnanofiberscaffoldforsofttissueandsofttissue-to-bonerepair,augmentationandreplacement358,859,802Compositionscontaining,methodsinvolving,andusesofnon-naturalaminoacidsandpolypeptides368,859,716Degradablethiol-enepolymers378,859,706Bioactivehydrogel388,858,925Pegylatedfibrinogenprecursormolecule398,858,698Acellularmatrixglue408,858,434Transcutaneousanalytesensor418,857,438Devicesandmethodsforacousticshielding428,853,361Preparation,foruse,inparticular,fortissueaugmentationandhealing438,853,294Polyurethane-graftedhydrogels448,853,278Compositionscomprisingabiocidalpolyamine458,853,184Polysaccharidegelformulationhavingincreasedlongevity468,846,894RNAinterferencemediatedinhibitionofgeneexpressionusingchemicallymodifiedshortinterferingnucleicacid(siNA)478,846,876Compositionscontaining,methodsinvolving,andusesofnon-naturalaminoacidsandpolypeptides488,846,357StabilizedchlorinedioxideforcontaminationcontrolinZymomonasfermentation498,845,600Skincarecompositionsandusesthereof508,845,578Biomaterialdeliverydevice518,845,536Transcutaneousanalytesensor528,845,535Devicefordetectingamedicalconditionordiseasea538,840,553Analytemonitoringdeviceandmethodsofuse548,840,552Membraneforusewithimplantabledevices558,835,573Biodegradablecompositesystemandtheusethereof568,835,144Dual-functionalnonfoulingsurfacescomprisingtargetbindingpartnercovalentlycoupledtopolymerattachedtosubstrate578,835,141Methodsforintegratedconversionoflignocellulosicmaterialtosugarsorbiofuelsandnano-cellulose588,834,951Dryglassycompositioncomprisingabioactivematerial598,834,917Nanoparticlecompositionandprocessthereof608,834,914Treatmentmethodsusingaparticulatecadavericallogenicjuvenilecartilageparticles618,834,913Medicalimplantsandmethodsofmakingmedicalimplants628,834,864Methodsforrepairingandregeneratinghumanduramater638,834,578Bioresorbableimplant648,834,522Biodegradableshapememorypolymericsutures658,829,110Nanocompositebiomaterialsofnanocrystallinecellulose(NCC)andpolylacticacid(PLA)668,829,097PLA-containingmaterial678,829,072Biomaterialcontainingdegradationstabilizedpolymer688,828,720Microcarriersforstemcellculture698,825,127Transcutaneousanalytesensor708,821,910Alkylaminoalkyloligomersasbroad-spectrumantimicrobialagent718,821,899Methodandprocessfortheproductionofmulti-coatedrecognitiveandreleasingsystems728,821,857Humanplacentalcollagencompositionsandmethodsofmakingandusingthesame738,821,835Flexibleand/orelasticbrachytherapyseedorstrand748,821,586Porousimplantgrainorgranul758,821,473Methodsandcompositionstotreatmyocardialconditions768,815,557Compositionsandmethodsforrefoldingofdenaturedproteins778,815,275Coatingsformedicaldevicescomprisingatherapeuticagentandametallicmaterial788,815,274Poly(esteramides)forthecontrolofagent-releasefrompolymericcompositions798,815,273Drugelutingmedicaldeviceshavingporouslayers808,814,819Glaucomatreatmentdevice818,813,847Hydraulicfracturing828,812,072Transcutaneousmedicaldevicewithvariablestiffness838,809,511Compositionscontaining,methodsinvolving,andusesofnon-naturalaminoacidsandpolypeptides848,809,273InhibitorsofBruton'styrosinekinase858,808,730Compositematerialfortissuerepair868,808,727Posteriorsegmentdrugdelivery878,808,725Solidformsfortissuerepair888,808,723Polymerscontainingpoly(esteramides)andagentsforusewithmedicalarticlesandmethodsoffabricatingthesame898,808,664Lipidatedglycoproteinparticlesandmethodsofuse908,808,531Smallvolumeinvitroanalytesensor918,808,342Nanoshelltherapy928,808,225Methodsanddevicesfordrugdeliverytooculartissueusingmicroneedle938,802,652Rehydratablepolysaccharideparticlesandsponge948,802,131Device