第一章 绪论 中药药剂学 英文讲义.doc

西安医学院教案课程名称中药药剂学班级 0902层次本科教师 陈程专业技术职务助教方式讲授课时2Chapter Chapter 1 IntroductionTeaching materialPharmaceutics of T.C.MPurpos： 1.Terms concerned2. the selection of dosage forms3. Property of pharmaceutics of T.C.MContent：1、 the property and task of pharmaceutics of T.C.M2、 Terms concerned3、 progress of pharmaceutics of TCM4、 the selection of dosage forms5、 others standardsTeaching method：teach。 Teaching tool ：MediaFocal and difficult points：1、the selection of dosage forms2、Terms concerned3、others standardsOpinions of teaching and research section： （Head of the TeachingResearch Section）2012.9.10ContentTIMEChapter 1 Introduction Section1 introduction the property and task of pharmaceutics of T.C.MProperty of pharmaceutics of T.C.M1、Definition：Pharmaceutics of T.C.M is a synthetical applied branch of science which studies the theories of preparation, techniques of manufacture, methods of quality control and clinical applications of preparations of T.C.M. with modern techniques under the guidance of the theory of the T.C.M. 2. Property under the guidance of the theory of the T.C.M. Contents: Pharmaceutical preparation and medicine compounding3、 Branch sciences of pharmaceutics industrial pharmaceutics physical pharmaceutics biopharmaceutics pharmacokinetics (clinical pharmacy)Tasks of pharmaceutics of TCM Terms concerned Dosage forms It is defined as the adequate forms of medicine in which the medicines is administrated.Section 2 History of pharmaceutics of TCM Survey of history of pharmaceutics of TCM Xia dynasty and Shang dynasty： Medicinal liquor、decoction¨ war states period “The Yellow Emperors Internal Classic”, which is the first medical and pharmaceutical ancient codex and literature in our nation, recorded some original dosage forms: decoctions, pills, powders, plaster, “danji”）, medicinal liquors, etc., and presented their making method, administration and indication. It was supposed a precursor of pharmaceutics. ¨ “Treatise on Febrile and Miscellaneous Diseases” ¨ “Synopsis of Prescriptions of the Golden Chamber” ¨ In Jin Dynasty, ¨ “A handbook of Prescriptions for Emergencies”, ¨ In Tang Dynasty ¨ “The Newly-Revised Materia Medica”, the earliest pharmacopoeia in the world.¨ In Song Dynasty, The first standard of pharmaceuticals appeared in 1080 A.D. “The Recipes of Taipinghuimin Pharmacy” ¨ The theory of pharmaceutics evolved in Jin and Yuan dynasty ¨ Ming and Qing dynasty¨ In Ming Dynasty: “Compendium of Materia Medica”, 1892 In Qing Dynasty: the formation of the Sect of Epidemic Febrile Diseases¨ Modern times ¨ progress of pharmaceutics of TCM new technology¨ 1、super-fine milling ：¨ 2、extration： ¨ （1）semi-bionic extraction method ¨ （2） supercritical fluid extraction method ¨ （3）ultrasonic wave extraction ¨ 3、separation technology¨ （1） membrane filtration¨ （2）Flocculation sedimentation ¨ （3）large pore resin adsorption（4）High speed centrifuge ¨¨ 4、concentration and drying technology¨ 5、 granulating technology：¨ 6、Coating ¨ Film coating ¨ 7、Solid dispersing technique ¨ new dosage forms ¨ the first generation¨ the second generation ¨ the third generation（sustain release）、 (controlled release) ¨ forth generation ¨ targeting preparation ¨ the fifth generationSection3 classification of dosage forms1、Classification according to physical phases 2、Dosage forms are classified by making methods: 3、 Dosage forms are classified by dispersion systems 4、Dosage forms are classified by the ways by which the drugs are administered. Section 4 the selection of dosage forms 1、 according to the clinical requirements 2、 according to the property of active components. 3、 according to the biopharmaceutics and pharmacokinetics property4、 according to manufacture facility and for convenience Pharmacopoeia and the standards 1.Pharmacopoeia definition of pharmacopoeia Pharmacopoeia is the national standard for drugs. It is compiled and promulgated by government. It is of legal authority. 2.Reviews of Chinese pharmacopoeia The first pharmacopoeia published by a government between 657-659 A.D. is “the Newly Revised Materia Medica” P.R.China Pharmacopoeia. (P.R.C.P.): Others (without legal authority): “Pharmacopoeia internationalis”(Ph.Int.) WHO：world health organization “European Pharmacopoeia”(Eur.Ph.) 3、The drug standard promulgated by The Public Health Ministry of P.R.C. 4、others standards（GMP）good manufacturing practice of drug （GLP）good laboratory practice of drug (GCP) good clinical practice of drug （GAP）good agricultural practice for chinese crude drugs （GSP）good supply practice 30min20min15min15min15min小结2min1.the property and task of pharmaceutics of T.C.M2.Terms concerned3.progress of pharmaceutics of TCM4.the selection of dosage forms复习题3min1.Terms concerned2.progress of pharmaceutics of TCM3.the selection of dosage forms教学后记评估：评教征求教师和学生意见评学下一节课前5分钟测试改进方法：时间利用：