单纯疱疹病毒高危评分.pdf

?单纯疱疹病毒感染症状：单纯疱疹病毒有、两个血清型，型大多引起腰以上的皮肤、眼、口唇疱疹，由口腔、呼吸道途径传播;型多引起腰以下和外生殖器皮肤疱疹及子宫颈粘膜疱疹，传播途径以性接触为主。胎儿和新生儿有关的主要是型。危险性：怀孕期间如果感染了单纯疱疹病毒，可造成胎儿宫内感染而致畸，如小头畸形、小眼球、视网膜发育不全及脑钙化等。“单纯疱疹病毒是最易侵犯人的一种病毒，在成年中单纯疱疹阳性的发生率为70%-80%，但在临床仅有一部分发病。”近年来，型单纯疱疹病毒感染的感染率呈不断上升趋势。陈敦金说：“孕妇由于体内激素水平的变化，及免疫低下，易受单纯疱疹病毒感染。”预防和对策：(1)虽然没有太多的预防办法，但至少在怀孕之前要减少性伴侣，洁身自爱。(2)妊娠前应进行单纯疱疹病毒的检查，如有感染应在妊娠前积极治疗，防止妊娠期及分娩时对胎儿的感染。(3)有明显外阴、阴道、宫颈单纯疱疹感染者，为预防新生儿经产道感染，应考虑做剖宫产手术。疱疹病毒感染主要由两性接触传播，患者也以1429 岁最多见。孕期由于孕激素增加，孕妇免疫力下降，孕妇感染是非孕妇的23 倍。现查明疱疹病毒感染除引起局部病变、宫颈炎症、继发感染和神经系统并发症外，还是宫颈癌的元凶，对成人特别是妇女的威胁很大。南京东大医学研究所疱疹病毒对胎儿的危害更严重。有人认为疱疹病毒感染对胎儿、新生儿是一种毁灭性疾病。许多报道指出，在孕早期感染(尤其是原发性感染者)病毒可通过胎盘引起胎儿病毒血症、自发性流产、死胎、先天畸形(主要是头小畸形和小眼畸形)、宫内发育迟缓及早产，也可呈隐性感染或持续带病毒状态等。大多数新生儿感染是因阴道分娩受染，虽然出生时外表可正常，但产后 3 周内逐渐出现症状。病状可有三种类型：一是疱疹型，只在皮肤、咽、眼结合膜等处出现疱疹；二是中枢神经型，表现为颅内压增高、抽搐等颅内感染的症状；三是全身性弥散型，表现为黄疸、肝炎、肺炎等全身毒血症症状。南京东大医学研究所未经积极处理的新生儿疱疹病毒感染，有50%80%可发生死亡或有神经系统后遗症，如小脑症、精神智能发育迟滞等。生殖器疱疹病的预防在于切断性传播疾病的传播途径。要隔离治疗病人及其配偶，努力减少传染来源。孕妇产前检查，必须详细询问病史，认真进行体格检查、细胞学检查及病毒培养等。一旦发现孕妇曾经或正在感染疱疹病毒，都需按高危产妇作特别加强监护。南京东大医学研究所如在孕期 28 周后患原发性感染，可行羊膜腔穿刺进行病毒培养，若培养为阳性，考虑胎儿患病毒血症，预后不良，应及时终止妊娠；若孕妇仅有局部损害，羊水培养阴性，可每周(或隔周)一次作宫颈分泌物培养，培养阴性者可考虑阴道分娩，培养阳性者宜作剖腹产分娩。剖腹产是避免新生儿感染疱疹病毒的有效方法，但手术时间的选择最好在羊膜破裂前施行，因为，羊膜破裂超过4 小时再行剖腹产，有94%的新生儿有发生感染的危险.因此，为避免不健康及智力低下儿的出生，一定要重视疱疹病毒感染的防治；孕妇生殖器疱疹病毒感染率比一般人高23 倍，而且病情较严重，治疗起来也比较难治，并且很多药物孕妇都禁用。孕妇感染生殖器疱疹不及时控制和治疗就会对胎儿造成严重的影响。怀孕初期的影响：母体怀孕早期染有这种病毒，病毒可通过胎盘侵犯胎儿，可对胎儿健康造成一系列的不良影响，引起胎儿诸多疾病，如病毒血症，造成胎儿畸形、胎儿宫内发育迟缓或死胎以及自发性流产等。轻度的感染也会造成胎儿在宫内发育迟缓，有些胎儿还可能发生各种畸形。孕妇分娩时的影响：孕妇分娩时是感染率很高的时期，型疱疹病毒存在于产道，通过产道传播可使50%左右的的新生儿被感染，且症状常较严重，重症患儿表现全泛发性水疙瘩，散发于全身皮肤、口腔和上呼吸道粘膜，重者可侵袭中枢神经文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3系统，以致出现高热、呼吸困难和出血，造成60-70%患儿死亡。经治疗痊愈而幸存的患儿，也会有高达85%的婴儿有后遗症。专家提示：在怀孕28 周内，疱疹病毒对胎儿影响最大，故发现后应终止妊娠。有生殖器疱疹病史的孕妇，在妊娠末期应进行型疱疹病毒培养，呈阳性者应做剖腹产。文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3寶貝儿问答历史疱疹病毒感染主要由两性接触传播，患者也以1429 岁最多见。孕期由于孕激素增加，孕妇免疫力下降，孕妇感染是非孕妇的23 倍。现查明疱疹病毒感染除引起局部病变、宫颈炎症、继发感染和神经系统并发症外，还是宫颈癌的元凶，对成人特别是妇女的威胁很大。南京东大医学研究所疱疹病毒对胎儿的危害更严重。有人认为疱疹病毒感染对胎儿、新生儿是一种毁灭性疾病。许多报道指出，在孕早期感染(尤其是原发性感染者)病毒可通过胎盘引起胎儿病毒血症、自发性流产、死胎、先天畸形(主要是头小畸形和小眼畸形)、宫内发育迟缓及早产，也可呈隐性感染或持续带病毒状态等。大多数新生儿感染是因阴道分娩受染，虽然出生时外表可正常，但产后3 周内逐渐出现症状。病状可有三种类型：一是疱疹型，只在皮肤、咽、眼结合膜等处出现疱疹；二是中枢神经型，表现为颅内压增高、抽搐等颅内感染的症状；三是全身性弥散型，表现为黄疸、肝炎、肺炎等全身毒血症症状。南京东大医学研究所未经积极处理的新生儿疱疹病毒感染，有50%80%可发生死亡或有神经系统后遗症，如小脑症、精神智能发育迟滞等。生殖器疱疹病的预防在于切断性传播疾病的传播途径。要隔离治疗病人及其配偶，努力减少传染来源。孕妇产前检查，必须详细询问病史，认真进行体格检查、细胞学检查及病毒培养等。一旦发现孕妇曾经或正在感染疱疹病毒，都需按高危产妇作特别加强监护。南京东大医学研究所如在孕期28 周后患原发性感染，可行羊膜腔穿刺进行病毒培养，若培养为阳性，考虑胎儿患病毒血症，预后不良，应及时终止妊娠；若孕妇仅有局部损害，羊水培养阴性，可每周(或隔周)一次作宫颈分泌物培养，培养阴性者可考虑阴道分娩，培养阳性者宜作剖腹产文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3分娩。剖腹产是避免新生儿感染疱疹病毒的有效方法，但手术时间的选择最好在羊膜破裂前施行，因为，羊膜破裂超过4 小时再行剖腹产，有 94%的新生儿有发生感染的危险.因此，为避免不健康及智力低下儿的出生，一定要重视疱疹病毒感染的防治文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 ZC4H3Y8G3K3文档编码:CD4V3F6E8F5 HS9L1K1I10J5 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