反刍动物霉菌毒素对食品安全 PPT课件.ppt
Mycotoxins in Ruminants for Food Safety反刍动物霉菌毒素对食品食品安全的危害 by Scott Fleetwood,Ph.D.Executive Director Global Industry and Government Policy and Affairs全球产业政策与政府事务执行理事，诺伟司国际公司A Safe Food Supply Is Critical食品安全是关键 Consumers must have a high level of trust that the food they eat is safe消费者必须高度信任他们所吃的食品是安全的Outbreaks of food borne diseases damage the reputation of the suppliers in the chain individually and collectively食源性疾病的爆发损害了食品供应链中个别或者全体供应商的声誉Understanding and implementing best practice processes will help ensure a safe food supply and trust with consumers around the world.理解和实施最佳食品安全生产管理将确保全球性的安全食品供应和消费者信赖The Novus Story诺伟司故事Born in 1991 out of the scientific heritage of Monsanto 成立于1991年，科技源于孟山都公司Growing under Mitsui&Co.(USA)Inc.and Nippon Soda Co,Ltd.成长于三井物产（美国）有限公司和日本曹达有限公司Multiple Product Families Based on Science 丰富的产品系列均基于科学的研究Portfolio Leveraged Across Multiple Species in Global Markets在全球市场跨越多个物种的产品组合Team of Industry Experts with Deep Market Knowledge 由具备深厚市场知识的行业专家组成的团队Programs Designed to Address Customer ROI&Challenge 旨在满足客户的投资回报率和解决问题的产品方案The Novus Story诺伟司故事Sales totaling 1.1 Billion USD 销售总额近1.1亿美元Over 900 employees around the world 全世界有900多名员工Conducting business in over 95 countries 业务遍及95个多国家Serving more than 2500 customers globally 服务全球2500多名客户Vision/远景景To help feed the world affordable,wholesome food and achieve a higher quality of life.为全球提供全球提供质优、价廉的健康食品，、价廉的健康食品，实现优质生活。生活。Mission/使命使命Make a clear difference in sustainably meeting the growing global needs for nutrition and health.在可持在可持续满足全球足全球营养和健康需养和健康需要上，作出要上，作出显著成著成绩。The Novus Story诺伟司故事生产性能动物福利食品安全环境保护护Food Safety Activity in China中国食品安全行动中国食品安全行动Mycotoxin occurrence in feed and feedstuffs of China in 2009中国饲料中的霉菌毒素污染情况,2009 All SamplesCorn FeedFermented Corn By-productWheat&Wheat BranSBM/CSM/RSMCo-occurrence of mycotoxins in 244 China samples(feed and feedstuffs),2009244种中国饲料和原料中霉菌毒素污染情况，2009No mycotoxins detected1 mycotoxin detected2 mycotoxins detected3 mycotoxins detected4 or more mycotoxins detectedFact:Some rumen microbes(and protozoa)degrade myxotoxins事实:反刍动物瘤胃微生物能降解霉菌毒素BUT BUT HOW MUCH?HOW MUCH?但是，降解多少？但是，降解多少？Natural Bioconversion in the Rumen瘤胃自发的生物转化能力Metabolized（降解）Non-Metabolized（未降解）Aflatoxin黄曲霉毒素0-42%58 100%Zearalenone玉米赤霉烯酮90%-Zearalenol 10 x more oestrogenic10%BUT oestrogenic metabolitesDON呕吐毒素35%Rumen-pH sensitive65%Ochratoxin A赫曲霉毒素AHigh?Jouany and Diaz 2005Ruminal Detoxification 反刍动物的解毒作用Sources of mycotoxins for ruminants反刍动物霉菌毒素的来源Feed supply-Grain 谷物饲料-Forage 干草料-Silage 青贮料-Pasture 牧草Bedding-Straw 稻草牛舍-Litter 垫料Dust灰尘AfB1ZONDONFUM B1T2positive%阳性检出率57.9 35.3 100.0 23.1 44.4 Average ppb平均值 ppb12 3716 559 602 156 median ppb中值 ppb12 942 306 361 115 Mycotoxin contamination in silage,hay and corn straw samples,China(n=19)中国青贮料，干草和秸秆霉菌毒素污染调查57.935.3100.023.144.4positive%AfB1ZONDONFUM B1T2-ToxinAflatoxin M1 Levels in Lactating Dairy Cattle哺乳期牛奶中黄曲霉毒素M1水平Diaz et al.Mycopathologia 2004添加黄曲霉毒素去除黄曲霉毒素天Feed:Milk=Feed:Milk=2%2%饲饲料：牛奶料：牛奶料：牛奶料：牛奶 =2%=2%China regulation:AFB1 limits in feed and feedstuffsGB 13078-2001，ppb中国政府对饲料及原料中黄曲霉毒素B1的浓度限制Feed typeAllowance（ppb）Corn 玉米50 Peanut meal,rapeseed meal,cotton seed meal 花生饼，菜籽，棉籽 Soybean meal 豆粕30 Dairy cattle concentration supplement 奶牛精料10 Beef cattle concentration supplement 肉牛精料50China regulation:OTA and ZON limits in feed and cornGB 13078.2-2006，ppb中国政府对饲料及玉米中赫曲霉毒素和玉米赤霉烯酮的浓度限制Feed typeAllowance（ppb）OTA赫曲霉毒素Compound feed,corn复合饲料，玉米 100ZON玉米赤霉烯酮Compound feed,corn复合饲料，玉米 500China regulation:DON limits in feedGB 130subtitil78.3-2008，ppm中国政府对饲料中呕吐毒素的浓度限制Feed typeAllowance(ppm)Compound feed for calf小牛复合饲料 1Compound feed for lactation animal泌乳期复合饲料 1Compound feed for cattle普通牛复合饲料 517What is a safe level of Mycotoxin?霉菌毒素的允许含量是多少？There are NO safe levels 没有允许含量Risk is dependent on the concentration 霉菌毒素的危害性程度取决于其存在的浓度Depends on the presence of other mycotoxins 取决于其他霉菌毒素存在与否18Mycotoxin management霉菌毒素管理Mycotoxins are the drop that fills the cup.They showcase deficiencies in production and management programs霉菌毒素的存在可以反应企业在生产和管理过程中存在的问题Subclinical losses are also key 无临床症状所造成的损失同样不容忽视Total nutrition综合营养管理方案Mineral/vitamin nutrition补充有机微量元素/维生素 Amino Acid nutrition补充氨基酸Gut health(MOS,Yeast,Organic Acids)维护肠道健康（MOS、酵母、有机酸）Feed quality/stability of nutrients(Vitamin E)确保营养物质的品质/稳定性（维生素E）Link between nutrition and health把营养与健康相结合Obrigado MerciGracias 谢谢谢谢 Asante sana mulumesccm n lmThank You!
