外文数据库上机实习报告(共11页).doc

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1、精选优质文档-倾情为你奉上外文数据库上机实习报告姓名：陶凤学号： 班级：商092班教师姓名：盛功平 1、利用Elsevier的Science Direct数据库检索： （1）、利用“快速检索”检索数字图书馆中的元数据研究这一课题的文献。关键词：数字图书馆（digital library）；元数据（metadata ）。要求：列出你的检索表达式；输出2-3篇题录式检索结果。检索表达式：digital library and metadata1Original Research ArticleLibrary Collections, Acquisitions, and Technical Serv

2、ices, Volume 30, Issues 1-2, March-June 2006, Pages 3-17Jin Ma| | | 2Original Research ArticleLibrary Collections, Acquisitions, and Technical Services, Volume 24, Issue 2, Summer 2000, Pages 217-227Kyle Banerjee| | | 3Original Research ArticleInformation Processing & Management, Volume 43, Issue 3,

3、 May 2007, Pages 740-751Muriel Foulonneau| | | （2）、利用“高级检索”检索关于药物上瘾治疗方法的研究，限定：关键词出现在“题名-摘要-关键词”字段，2002年以来发表的文章，限定在医学领域内查找。关键词：药物（drug）、上瘾（addiction）、治疗方法（therapy）；要求：列出你的检索表达式和检索步骤；列出2-3篇文摘式检索结果。检索表达式和检索步骤：进入安徽工业大学图书馆网页，点击Elsevier数据库，进入页面，检索表达式为drug and addiction and therapy.点击searchArticle in Press

4、, Corrected Proof - |Copyright 2010 Socit franaise de psychologie Published by Elsevier Masson SAS Article originalExiste-t-il une typologie familiale dans les pathologies addictives? Revue critique de la littrature sur les familles dadolescents prsentant des troubles alimentaires ou des conduites d

5、e dpendance aux substances Is there a family typology of addictive behaviors? Critical review of the literature in the families of adolescents with an eating disorder or with a substance-dependence K. Doba, , , and J.-L. Nandrino, , a EA1059, unit de recherche en sciences cognitives et affectives (U

6、RECA), universit Lille-3, 35, rue Sainte-Barbe, BP 70460, 59208 Tourcoing, FranceReceived 7 June 2010; accepted 16 October 2010. Available online 20 November 2010. RsumParmi les facteurs favorisant les conduites addictives, certaines caractristiques du fonctionnement familial sont souvent voques dan

7、s les troubles alimentaires et dans les dpendances aux substances psychoactives ou lalcool. La mise lpreuve des observations des processus familiaux par des recherches empiriques intgrant diffrents niveaux pistmologiques et mthodologiques a conduit des rsultats contradictoires concernant les diffren

8、tes formes de fonctionnements familiaux associs ces pathologies addictives. Cet article propose une revue critique de la littrature dans le cadre des conceptions systmiques concernant les drglements familiaux impliqus dans lapparition des troubles alimentaires et des dpendances aux substances ou lal

9、cool chez les adolescents. Il sagira galement de discuter la similarit des caractristiques familiales entre ces pathologies addictives et lhypothse dune typologie familiale propre aux conduites addictives.AbstractAmong factors favoring the addictive behaviors, some specific family processes are ofte

10、n identified in eating disorders and dependences with psychoactive substances. Different models of systemic orientation described the familial disturbances involved in the addictive pathologies emphasizing either the emotional interaction and the processes of differentiation family, either the struc

11、ture and the level of family cohesion. This article proposes a critical review of the systemic literature on the familial disturbances involved in the families of adolescents with eating disorders or with a substance-dependence. The systemic models (Bowen, Minuchin) are reference values in the under

12、standing of family processes and therapy with families. The observations of these family processes have been confronted to empirical researches integrating different epistemological levels and different methods. The empirical results are heterogenous concerning the different forms of family function

13、ing associated with these addictive pathologies. The empirical studies support the hypothesis of a family dysfunctioning in the different addictive behaviors and demonstrate the relationship between the severity of familial disorders and the severity of the addictive disorders. However, the family c

14、onfiguration described by the typological models is rarely found complete or with a similar intensity between the families. The studies support the hypothesis of an emotional distance in the family interactions and a lack of parental care which could correspond to factors of chronicity or vulnerabil

15、ity. Comparing the family characteristics of these two types of addictive behaviors, the literature supports the existence of (1) some specific family characteristics according to the type of addictive behavior (in particular the conflict avoidance which appears specifically in anorexic families) (2

16、) some similar family patterns of interactions between the members of addictive families in particular the representation of a low family cohesion, an intergenerational enmeschment and a high level of control. These family patterns suggest rather to a dimensional approach of the family characterized

17、 by different protective or risk factors. We suggest that these family patterns could constitute, according to their importance (intensity and frequence), a family risk factor of development or aggravation of the addictive behaviors.Mots cls: Addiction; Troubles alimentaires; Dpendances aux substanc

18、es; Adolescence; FamilleKeywords: Addiction; Eating disorders; Drug dependence; Adolescence; FamilyArticle Outline12.2.1. 2.2. 33.1. 3.1.1. 3.1.2. 3.1.3. 3.1.4. 3.2. 3.2.1. 3.2.2. 3.2.3. 3.2.4. 3.2.5. 3.2.6. 4. Article in Press, Uncorrected Proof - |Copyright 2010 Published by Elsevier Inc. Psychoph

19、armacological comparison of schizophrenia spectrum disorder with and without cannabis dependency Zoltan Makkos, Lilla Fejes, Gabriella Inczdy-Farkas, Akos Kassai-Farkas, Gabor Faludi and Judit Lazary, , a 1st Department of Psychiatry, Nyr Gyula Hospital, Budapest, Hungaryb Centre of Molecular Neurol

20、ogy, Semmelweis University, Budapest, Hungaryc Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, HungaryReceived 24 July 2010; revised 2 October 2010; accepted 5 November 2010. Available online 16 November 2010. AbstractBackgroundAlthou

21、gh incidence of schizophrenia is higher among cannabis users and marijuana is the most common abused drug by adolescents, etiological linkage between schizophrenia and cannabis use is still not clarified. Clinical experiences suggest that regular cannabis user can show similar psychotic episode to s

22、chizophrenic disorders but it is still unclear if chronic cannabis use with schizophreniform disorder is a distinct entity requiring special therapy or it can be treated as classical schizophrenia. There are no data available on the comparison of pharmacotherapy between schizophreniform patients wit

23、h and without cannabis use.MethodsClinical data of 85 patients with schizophrenia spectrum disorder were analyzed retrospectively. Cannabis use was not reported by 43 persons (Cnbs0 subgroup) and 42 patients used regularly cannabis during at least 1year (Cnbs1 subgroup). Comparison of anamnesis, fam

24、ily history, social-demographic condition, positive and negative symptoms, acute and long-term therapies recorded by clinical interviews was performed with chi square tests, logistic binary regression and t-tests using SPSS 13.0 for Windows software.ResultsMen were over-represented in cannabis depen

25、dent group while mean age was lower among them compared to Cnbs0 subgroup. Prevalence of suicidal attempt was increased in men without cannabis use (OR=5.25, p=0.016). Patients without cannabis use spent more time in hospital (p=0.026) and smoking was more frequent among them (OR=1.36, p=0.047). The

26、 chance to get olanzapine for acute therapy and aripiprazol for long term therapy was more than two fold in Cnbs1 subgroup (OR=2.66, OR=3.67, respectively). However, aripiprazol was used for acute therapy with significantly lower risk in Cnbs1 subgroup (OR=0.47, p=0.023). Olanzapine was administered

27、 for long term therapy in a higher dose to Cnbs0 patients (p=0.040). Also higher dose of risperidon LAI was used in women without cannabis dependency compared to women of Cnbs1 subgroup (p=0.020). Positive and negative symptoms and family history did not differ significantly between the two subgroup

28、s.ConclusionAlthough symptom profile was similar, hospitalization time, suicidal anamnesis, smoking habit and also dosage, intensity and lasting of therapy were different between the two subgroups. Further prospective studies are required for the investigation of the clinical and molecular backgroun

29、d of this discrepancy in order to determine a relevant protocol of prevention and treatment of the chronic cannabis use related psychotic disorder.Research HighlightsThis is the first complex clinical comparison including pharmacotherapy between schizophrenia with and without cannabis use. We found

30、that although symptom profile was similar, hospitalization time, suicidal anamnesis, smoking habit and also dosage, intensity and lasting of therapy were different between the two subgroups. Our data suggest that besides shared components, vulnerability for cannabis use and schizophrenia and maybe a

31、lso for addictive disorders may have different pathogenetic factors, consequently altered molecular background and alternative pharmacological response.Keywords: Addiction; Cannabis; Psychosis; Psychopharmacotherapy; THCAbbreviations: CB1, cannabinoid receptor 1; CGI-S, Clinical Global Impression Sc

32、ale; CGI-I, Clinical Global Improvement Scale; Cnbs, cannabis; HPDC, haloperidol decanoate; LAI, long acting injections; OR, odds ratioArticle Outline12345. 2、利用EI 数据库“快速检索”检索铝合金表面激光溶覆研究，关键词：铝合金（Aluminum alloy）；激光溶覆（laser cladding），限定：在“主题/题名/摘要”字段中进行检索；时间是2000年以来发表的文章。要求：列出你的检索表达式和检索步骤，列出2-3篇文摘式检索结

33、果。检索表达式和检索步骤: 进入安徽工业大学图书馆网页，点击EI 数据库,进入页面。检索表达式：Aluminum alloy and laser cladding, January 2011, Pages 49-53 |Copyright 2010 Elsevier Ltd All rights reserved. Microstructure characteristics of Ti3Al/TiC ceramic layer deposited by laser cladding Li Jianing, Chen Chuanzhong, , and Zong Leia Key Labora

34、tory for Liquid-Solid Structural Evolution and Processing of Materials (Ministry of Education), Department of Materials Science, Shandong University, Jinan , PR ChinaReceived 18 April 2010; accepted 8 July 2010. Available online 15 July 2010. AbstractAl+TiC laser cladding coatings were prepared on T

35、i6Al4V alloy by CO2 laser cladding technique. The microstructure, micro-hardness and phase constitutes of the laser cladding layer were investigated by means of scanning electron microscope (SEM), X-ray diffraction (XRD) and microsclermeter. The results indicated that the laser cladding layer solidi

36、fied into the fine microstructure rapidly, and TiC hard phase was dispersived in the cladding layer. When the mass percent of TiC was 40%, the micro-hardness (1100HV0.21250HV0.2) of Al+TiC cladding layer was 3 times more than that of the Ti6Al4V alloy substrate (350370HV0.2). The cladding layer main

37、ly consisted of -Ti (Al), -Al (Ti), Ti3Al, TiAl, Al3Ti and TiC phase. There phases were beneficial to improve the hardness and wear resistance of the cladding layer.Keywords: Titanium alloy; Laser cladding; Surface modification; Microstructure; Phase constituteArticle Outline122.1. 2.2. 33.1. 3.2. 3

38、.3. 4, 15 October 2009, Pages 2392-2397 |Copyright 2009 Elsevier B.V. All rights reserved. Anti-tumor activity of paclitaxel-loaded chitosannanoparticles: An in vitro study Fang Li, , , Jianing Li, Xuejun Wen, , , Shenghu Zhou, Xiaowen Tong, Pingping Su, Hong Li and Donglu Shi, , aDepartment of Obst

39、etrics and Gynecology, Affiliated Tenth Hospital, Tongji University, Shanghai, , Peoples Republic of ChinabThe Institute for Advanced Materials and Nano Biomedicine, Tongji University, Shanghai, , Peoples Republic of ChinacDepartment of Bioengineering, Clemson University, Charleston, SC, 29425, USAd

40、Department of Chemical & Materials Engineering, University of Cincinnati, Cincinnati, OH, 45221-0012, USAReceived 3 June 2009; accepted 5 July 2009. Available online 12 July 2009. Referredtoby:Materials Science and Engineering: C, Volume 30, Issue 4, 10 May 2010, Page 644, Fang Li, Jianing Li, Xueju

41、n Wen, Shenghu Zhou, Xiaowen Tong, Pingping Su, Hong Li, Donglu Shi |AbstractChitosan nanoparticles containing the anticancer drug paclitaxel were prepared by a solvent evaporation and emulsification crosslinking method. The physicochemical properties of the nanoparticles were characterized by vario

42、us techniques, and uniform nanoparticles with an average particle size of 11615nm with high encapsulation efficiencies (EE) were obtained. Additionally, a sustained release of paclitaxel from paclitaxel-loaded chitosan nanoparticles was successful. Using different ratios of paclitaxel-to-chitosan, t

43、he EE ranged from 32.28.21% to 94.016.73 %. The drug release rates of paclitaxel from the nanoparticles were approximately, 26.552.11% and 93.4410.96% after 1day and 13days, respectively, suggesting the potential of the chitosan nanoparticles as a sustained drug delivery system. Cytotoxicity tests s

44、howed that the paclitaxel-loaded chitosan had higher cell toxicity than the individual paclitaxel and confocal microscopy analysis confirmed excellent cellular uptake efficiency. TEM images showed the ultrastructure changes of A2780 cells incubated with paclitaxel-loaded nanoparticles. Flow cytometr

45、ic analysis revealed two subdiploid peaks for the cells in the paclitaxel-loaded nanoparticles and paclitaxel treated groups, respectively, with the intensity of the former higher than that of the latter. Moreover, the cell cycle was arrested in the G2-M phase, which was consistent with the action m

46、echanism of the direct administration of paclitaxel. These results indicate that chitosan nanoparticles have potential uses as anticancer drug carriers and also have an enhanced anticancer effect.Keywords: Chitosan; Nanoparticles; Paclitaxel; Sustained release; Ovarian cancerArticle Outline122.1. 2.2. 2.3. 2.4. 2.5. 2.6. 2.7. 2.8. 2.9. 2.10. .33.1. 3.2. 3.3. 3.4. 3.5. 3.6. 3.7. 4专心-专注-专业