LED 灯具 光电集成电路 新材料 生物质能源(8页).doc

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1、-LED 灯具 光电集成电路 新材料 生物质能源-第 8 页CIRP Annals - Manufacturing TechnologyThe extending responsibility of manufacturers regarding their products environmental impact has led to the development of a wide range of Life Cycle Engineering tools and techniques. However, their efficiency has yet been limited by

2、 the need for detailed input data, typically unavailable in the early conceptual phases of design, when most far-reaching improvements can be achieved. This problem particularly holds true in a design environment of one-of-a-kind products, such as in many automation and machine design projects, wher

3、e no previous generation products are available to provide the required analysis feedback. This paper presents a set of pro-active support tools that are specifically developed for the early design phases and cover the analytical as well as the creative steps of design. On the one hand, Eco-Cost Est

4、imation Relationships form the core of the Eco-PaS system, which estimates the technical parameters, needed as input for most assessment tools, as a function of the functional parameters available in the concept development phase. On the other hand, the Ecodesign Knowledge System classifies both kno

5、wledge and user situations according to a common set of domain models in order to supply, at any time, adequate Life Cycle Engineering guidance, tailored to the specific user situation.Psychotherapy: Theory/Research/Practice/TrainingThe proliferation of computer-mediated communication has led to the

6、 experimentation with these tools in psychotherapy. This article examines the possible integration between traditional and new tools in psychotherapy, showing pros and cons of the use of technology. In particular, the article focuses on the concept of e-therapy and the technology it requires. An ana

7、lysis of the most functional tools and software now available is also presented, with a particular focus on shared hypermedia, new Internet tools in which different users who are simultaneously browsing the Web can communicate and surf together.Bioorganic & Medicinal Chemistry LettersGraphical abstr

8、actTo achieve high bioavailability towards the design of Helicobacter pylori antibacterial drugs, a pro-drug approach was implemented wherein a sulfoxide moiety is oxidized in vivo to the more potent sulfone.Medical Laser ApplicationLED therapy accelerates healing post-resurfacing. Laser ablative re

9、surfacing is still the most effective method for the rejuvenation of severely photoaged and photodamaged facial skin, but the long-healing time coupled with other troublesome sequelae mean a long patient downtime. Phototherapy with light-emitting diodes (LEDs) has recently been attracting attention

10、in accelerating wound healing. The current study was designed to assess the beneficial effects of LED phototherapy on wound healing and postoperative sequelae following laser ablative resurfacing. The study had both a prospective and retrospective arm. The prospective study population consisted of 2

11、8 female patients who underwent ablative Er:YAG/CO2 laser resurfacing (four full face, eight periocular, 16 perioral), followed by hemifacial LED therapy with 830nm followed by 633nm LED panels, 20min/session (55 and 98J/cm2, respectively. The contralateral side of the face was covered with an opaqu

12、e material to prevent exposure to the LED energy. A similar number of age- and treatment-matched patients previously treated in the same way, but without LED therapy, formed the retrospective arm. Tissue healing time and postoperative sequelae were compared for the treated and untreated sides in the

13、 prospective group and for the untreated retrospective group. The healing time in the LED-treated side was around 50% faster and sequelae significantly less compared with the untreated side, but interestingly these factors were slightly better in the untreated side compared with the retrospective un

14、treated controls. At a 6-month follow-up in the prospective group, no significant difference in wrinkle improvement was seen between the treated and untreated side, but the skin appeared younger-looking on the LED-treated compared with the untreated side. Combined LED therapy significantly improved

15、healing time and treatment sequelae in laser ablative resurfaced photoaged facial skin. It appears that this combined LED therapy approach may also help to sustain the good results through a maintenance therapy program.ZusammenfassungResurfacing durch Laserablation ist noch immer das wirksamste Verf

16、ahren zur Verjngung stark lichtgealterter und lichgeschdigter Gesichtshaut, doch die lange Wundheilung und andere lstige Folgeerscheinungen bedeuten eine erhebliche Ausfallzeit fr den Patienten. Bei der Beschleunigung der Wundheilung ist man krzlich auf die Phototherapie mit lichtemittierenden (LED-

17、) Dioden aufmerksam geworden. Im Rahmen der vorliegenden Studie sollten die positiven Auswirkungen der LED-Phototherapie auf die Wundheilung und postoperative Folgeerscheinungen nach Laser-Resurfacing evaluiert werden. Die Studie bestand aus einem prospektiven und einem retrospektiven Teil. Die pros

18、pektive Gruppe bestand aus 28 weiblichen Patienten, die mit dem Er:YAG/CO2-Laser (4gesamtes Gesicht, 8periocular, 16perioral) behandelt wurden und sich anschlieend einer hemifazialen LED-Therapie bei 830nm sowie einer Behandlung mit 633nm-LED-Platten unterzogen. Die Behandlungsdauer pro Sitzung betr

19、ug 20min bei 55J/cm2bzw. 98J/cm2. Die kontralaterale Gesichtsseite wurde mit strahlenundurchlssigem Material abgedeckt, um sie vor der LED-Energie zu schtzen. Die retrospektive Gruppe bestand aus einer gleichen Anzahl von Patienten passenden Alters, die zuvor die gleiche Behandlung, jedoch ohne LED-

20、Therapie, erfahren hatten. Gewebeheilungsdauer und postoperative Folgeerscheinungen fr die behandelten und unbehandelten Seiten in der prospektiven Gruppe s.u. wurden miteinander verglichen. Die Wundheilungszeit der LED-behandelten Seite war um etwa 50% krzer und die Folgeerscheinungen waren signifi

21、kant geringer als bei der unbehandelten Seite, aber diese Faktoren waren interessanterweise bei der unbehandelten Seite etwas besser als im Vergleich zur retrospektiven unbehandelten Kontrollgruppe. Bei einer Nachuntersuchung der prospektiven Gruppe nach 6 Monaten fand sich zwischen behandelter und

22、unbehandelter Seite kein signifikanter Unterschied in der Faltenreduktion, aber im Vergleich zur unbehandelten Seite erschien die Haut der LED-behandelten Seite jnger aussehend. Die kombinierte LED-Behandlung verkrzte die Heilungsdauer und die minderte Folgeerscheinungen des Laser-Resurfacing von li

23、chtgealterter Gesichtshaut signifikant. Es scheint, dass dieser Kombi-LED-Therapieansatz auch dazu beitragen knnte, die positiven Ergebnisse durch ein Erhaltungstherapieprogramm zu verstrken. ResumenLa tcnica de Resurfacing mediante el uso de lser ablativo continua siendo el mtodo ms eficaz para el

24、rejuvenecimiento de la piel facial severamente foto daada o foto envejecida, a pesar de que el largo perodo de curacin junto a otros efectos problemticos luego del tratamiento, implican una prolongada inactividad del paciente. Recientemente, el uso de la fototerapia con LEDs (Diodos de Emisin de Luz

25、) ha ganado importancia para la aceleracin del proceso curativo. El presente estudio fue diseado con el fin de determinar los efectos beneficiosos de la fototerapia LED en la recuperacin de las lesiones y las secuelas postoperatorias luego del resurfacing con lser ablativo. Para ello, se incluyeron

26、datos prospectivos y retrospectivos. El estudio prospectivo fue realizado en 28 pacientes mujeres, sometidas a un tratamiento de resurfacing utilizando el lser ablativo Er:YAG/CO2 (4 cara completa, 8 periocular, 16 perioral), seguido de una terapia LED hemifacial, con pases LED de 830nm y 633nm, 20m

27、in/sesion (55J/cm2y 98J/cm2), respectivamente. El lado contralateral de la cara fue cubierto con un material opaco para prevenir la exposicin a la energa del LED. Para el estudio retrospectivo se incluy un grupo de pacientes de edad similar sometidas a un tratamiento comparable, pero sin terapia LED

28、. Se compar el tiempo de recuperacin del tejido y las secuelas postoperatorias de las pacientes del grupo prospectivo en los lados de la cara tratado y no tratado, y las pacientes no tratadas del grupo retrospectivo. El tiempo de recuperacin en el lado tratado con LED fue aproximadamente un 50% ms r

29、pido y la cantidad de secuelas postoperatorias fueron significativamente menores a las determinadas para el lado no tratado. Sorprendentemente, estos factores presentaron incluso una leve mejora en el lado no tratado comparado con las pacientes sin tratamiento del estudio retrospectivo. En el seguim

30、iento de seis meses del grupo prospectivo no se encontr diferencia significativa en el mejoramiento de las arrugas en los lados tratado y no tratado, aunque la piel en el lado de la cara tratado con LED presentaba un aspecto ms rejuvenecido. El tratamiento combinado conn LED acort el tiempo de recup

31、eracin y redujo perceptiblemente los resultados del resurfacing con lser ablativo de la piel facial foto envejecida. Aparentemente el uso de esta terapia combinada con LED contribuira a preservar los buenos resultados mediante un programa de terapia de mantenimiento.Article OutlineLED灯光/灯具治疗与疗养/室内外皮

32、肤养护产品 设计开发及其原理与安全性的初步分析植物的光合作用机理及其功能蛋白质分析Analytical BiochemistryChromatography supports to purify phosphorylated proteins (P-proteins) have become available recently, yet this has not been thoroughly investigated in the case of plant materials. In this study we used a commercial affinity matrix (Qia

33、gen) and a test plant enzyme (phosphoenolpyruvate carboxylase PEPC). The malate test and gel blot experiments probed with a specific antibody (antiphosphorylated N-terminal domain) showed that the column efficiently binds P-PEPC from Sorghum with little or no contamination by non-P-PEPC. Similar res

34、ults were obtained with the low-abundance PEPC of Arabidopsis leaves when a gel filtration step (Sephadex G-200) was performed prior to the chromatography. Three-dimensional mass spectrometry analysis of immunoprecipitated PEPC in Qiagen fractions confirmed this observation. Denaturing protein extra

35、ction by cold acetone/trichloroacetic acid of fixed material led to a complete, one-step separation of P-PEPC and non-P-PEPC. At a global scale, the column captured most of the 32P-phosphate-labeled proteins in vivo (80%), the majority of which were subsequently found in the elution fraction (88%).

36、This was also visualized by SDSPAGE (1D and 2D gels) followed by Pro-Q diamond staining. Analysis of the P-protein fraction by 1D gels and liquid chromatography/tandem mass spectrometry allowed the identification of 250 proteins belonging to various functional categories. These results validate the

37、method for in vitro/in vivo studies of native/denatured individual proteins/enzymes regulated by phosphorylation and for phosphorylome studies.Article OutlineAppendix A. 分析生物化学学报Robotics and Computer-Integrated ManufacturingInformation-theoretic modelling of manufacturing organizations and their sup

38、ply chains has led to the development of measures of manufacturing complexity. The measures include assessment of the structural, dynamic and decision-making complexity associated with the processing and movement of material and information around a manufacturing system. A computer program has been

39、written to calculate the decision-making complexity of a manufacturing system, under different system layouts and operating characteristics. In order to make the results of this program accessible to manufacturing organizations, an expert system has been developed to act as a mediator between the pr

40、ogram and interested organizations. Given some simple quantitative data on manufacturing performance, the expert system can estimate the organizations complexity and suggest some recommendations to reduce it, based on the data provided by the organization. The expert system will be implemented on th

41、e web to enable on-line acquisition and searching of data on companies. The quid pro quo of the expert system is that anonymized data on the organizations will be retained so that complexity benchmarks may be established.Article Outline机器人与计算机集成制造系统学报基于网络的租用/共用复杂制造设备/设施 开放式柔性化生产车间的设计Bioresource Tech

42、nologyAbstractThe use of biomass to provide energy has been fundamental to the development of civilisation. In recent times pressures on the global environment have led to calls for an increased use of renewable energy sources, in lieu of fossil fuels. Biomass is one potential source of renewable en

43、ergy and the conversion of plant material into a suitable form of energy, usually electricity or as a fuel for an internal combustion engine, can be achieved using a number of different routes, each with specific pros and cons. A brief review of the main conversion processes is presented, with speci

44、fic regard to the production of a fuel suitable for spark ignition gas engines.农作物/庄家的本地化（本土化）与外来物种的侵扰（入侵）和交互影响Basic and Applied EcologyThe process of crop domestication involves artificial selection for beneficial traits in plants, such as yield, standard development times for ease of harvest, and

45、pest and disease resistance. This process has greatly improved crop performance and can allow farmers to produce viable harvests in previously un-profitable circumstances. However, there is growing evidence that domestication may impact species interactions perhaps through the amplification of effec

46、ts across spatial scales and so have a pervasive influence on the functioning and sustainability of agro-ecosystems. This can occur directly, through unintentional alteration to crop traits that disrupt the host-finding ability of natural enemies; or indirectly through alterations to within-plant nu

47、tritional quality that impacts herbivore size and density and then ramifies throughout food chains. At the field level, the low variability in traits between individual plants means that particular weed and invertebrate communities are associated with each crop type. At the landscape level, the use

48、of one or a few varieties across wide spatial scales, planted and harvested relatively synchronously, further reduces diversity. This process acting across multiple spatial scales represents a considerable selection pressure that may result in feedback-loops which favour the occurrence of particular

49、 traits within the community (e.g. resistance to pesticides). In order to properly balance the pros and cons of the widespread adoption of new varieties, for the future, we must consider how particular traits influence interactions within the wider ecological community, and how these effects amplify across spatial scales. Here we argue that the process of domestication (with