奥美拉唑与法莫替丁治疗消化性溃疡72例疗效对比-法莫替丁治疗消化性溃疡的机制是.docx
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《奥美拉唑与法莫替丁治疗消化性溃疡72例疗效对比-法莫替丁治疗消化性溃疡的机制是.docx》由会员分享,可在线阅读,更多相关《奥美拉唑与法莫替丁治疗消化性溃疡72例疗效对比-法莫替丁治疗消化性溃疡的机制是.docx(7页珍藏版)》请在淘文阁 - 分享文档赚钱的网站上搜索。
1、奥美拉唑与法莫替丁治疗消化性溃疡72例疗效对比:法莫替丁治疗消化性溃疡的机制是 R573 A 16723783(2011)05031302 目的探讨奥美拉唑治疗消化性溃疡的临床疗效。方法选择72例消化性溃疡患者,随机分为两组,治疗组采纳奥美拉唑联合阿莫西林和克拉霉素治疗,比照组采纳法莫替丁联合阿莫西林和克拉霉素治疗,比较两组治疗临床疗效。结果治疗组痊愈22例,显效6例,进步5例,无效3例;比照组痊愈11例,显效6例,进步11例,无效8例。两组临床疗效比较组间资料采纳fisher检验,P=0.04360.05,两组资料比较差异有统计学意义。两组痊愈病例随访6个月,治疗组治疗组痊愈22例,复发3例
2、,比照组痊愈11例,复发6例,两组比较组间资料采纳fisher检验,P=0.03340.05,两组资料比较差异有统计学意义。结论采纳奥美拉唑联合阿莫西林和克拉霉素其效果优于法莫替丁联合阿莫西林和克拉霉素的治疗,收到了很好的效果。 奥美拉唑 消化性溃疡 Clicical Observe of Omeprazole and famotidine in Treating 72 peptic ulcer Objective Investigate the clinical efficacy of omeprazole treatment of peptic ulcer. Methods 72 case
3、s of peptic ulcer were randomly divided into two groups combined treatment group omeprazole amoxicillin and clarithromycin treatment, the control group with combined famotidine treatment of amoxicillin and clarithromycin, compare the two Clinical efficacy of treatment group. Result Treatment of 22 c
4、ases were cured, markedly effective in 6 cases, progress in 5 cases, 3 cases; control group, 11 patients cured, markedly effective in 6 cases, progress in 11 cases, 8 cases. Clinical efficacy data were compared between groups using fisher test,P=0.0436 0.05, difference between the two groups was sta
5、tistically significant data. Two groups of recovered patients were followed up for 6 months, treatment group, 22 cases were cured, recurrence in 3 cases, the control group healed in 11 cases, 6 cases of recurrence in both groups data were compared between groups using fisher test,P=0.03340.05, two s
6、ets of data The difference was statistically significant.Conclusion Omeprazole combined with amoxicillin and clarithromycin is superior to the United famotidine amoxicillin and clarithromycin treatment, received very good results. Omeprazole; peptic ulcer 消化性溃疡(Peptic ulcer PU)是临床上常见的消化系统疾病,病程较长,主要是
7、指发生在胃与十二指肠部位的慢性溃疡,主要的临床症状表现为腹痛、上腹胀、反酸、嗳气等。消化性溃疡的发病率占到总人口的1012%,常见于青壮年和老年患者,由于其发病的缘由与发病机理相当困难,因此其治疗的有效率虽高,复发率也很高1。幽门螺旋杆菌(helicobacterpylori,Hp)感染是导致消化性溃疡的重要因素之一,有报道称,根除Hp能够使十二指肠球部溃疡和胃溃疡的复发率降到5% 以下2。我们选择2009年10月2010年10月期间治疗的72例消化性溃疡患者进行临床疗效分析,现报道如下。 1 资料与方法 1.1 一般资料:选取2009年10月2010年10月我科收治的消化性溃疡患者72例,其
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