《诊断学总论》PPT课件.pptx

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1、Clinical DiagnosticsCHINA MEDICAL UNIVERSITYZHAO LI Physical Diagnosis Todays medical Todays medical studentsstudents Tomorrows cliniciansTomorrows cliniciansPhysical DiagnosisWhat is the meaning of “Clinician”?Physical DiagnosisWhat is the main responsibility of the clinician?Making diagnosis Treat

2、 a disease Treat a patientPhysical DiagnosisA linkage between basic medical knowledge and clinical medicine.A discipline to use basic medical theory and skill to make a diagnosis.Obtain informationFrom any and every source possible.Strain to hear the voice of the patient in the thin reed of his cryi

3、ng.See most acutely out of the corner of your eye.To hear best with your inner ear.The contents of diagnosisVerbal observation or history takingPhysical observation or examinationLaboratory observationHistory TakingObtain as much information as needed to diagnose and treat the illness.Requirements f

4、or the physicians:A genuine,profound,and absorbing interest in the patients well beingA deep-seated,well-grounded self confidence in abilities A through knowledge of the diseases Ability to see the problem from the patients viewpointHistory TakingObtaining a medical history is an artTalk with,rather

5、 talk to the patient.Listen attentively and guide a patient effectively.Ask searching questions.Interrogation of family and friends if necessary.History TakingKnow all about the diseaseSymptoms and signsSymptoms:patients complaints,or his recognition of something abnormal.Signs:findings elicited by

6、physical examinationPast historyFamily history Systems reviewPhysical ExaminationBegins when greeting the patient.Sedulously practicing the art of observation make a student to a clinician.How to conduct physical examinationApplication of the sensory end organ to the patient.In a rational,thorough,a

7、nd accurate fashion.With efficiency and minimal discomfort to the patient.5 components of physical examination:inspection,palpation,percussion,auscultation and smelling.Laboratory findingsTo detect pathogenic or functioning information.Chemical,biological and physiological tests.X-film,CT,MR.gastros

8、copy,angiography and bronchoscopy etc.Interpretation of laboratory dataLots variables alter laboratory tests results.Specificity and sensitivity of the tests.Overlapping between the healthy and the diseased subjects.The Intellectual process of diagnosisInformation requires clarification and amplific

9、ation.Information must be carefully weighed as to its clinical significance and its possible relationship to the patients complaints6 levels of intellectual functioning：knowledge,comprehension,application,analysis,synthesis,and evaluation6 levels of intellectual functioningKnowledgeUnedited factual

10、information provided by the patient.May not necessarily be accurate or precise.ComprehensionUnderstanding the facts related by the patient.Affirm what the patient said.ApplicationRecording the facts accurately and in a well-organized order6 levels of intellectual functioningAnalysisSorting out or cl

11、assification of the obtained data into related categories.SynthesisReassemble the data obtained into patterns of recognizable disease.EvaluationAsking questions that are designed to either confirm or exclude tentative diagnoses.Predicting the likely physical and laboratory finding.The role of high t

12、echnologyAlways be a tool.Can never replace the intellectual process of diagnosis.The role of high technology Patient is a human being,not a Patient is a human being,not a machine!machine!Physician is a medical detective,not a Physician is a medical detective,not a detector!detector!ConclusionCommun

13、ication，observation and data recording are the key demands in medicine.Profound knowledge and smart intellectual process of thinking of medicine is the key for success of a clinician.Only as a clinician does one become a clinicianWhat is Clinical Diagnostics?Fundamental theory Techniques of diagnosi

14、ng disease Mode of clinical thinking What is Clinical Diagnostics?Instruct a concise logical approach to recognize the genius of the diseasesA fundamental course of clinical medicineFundamental elements of DiagnosticsDiagnosis Identification Analysis Diagnosis Derived from Greek words distinguish or

15、 discern English term DiagnosticThe distinguishing sign and symptoms with which it gerenally begins,continues and goes offas it were,a history of the disease In 18th century:Nosography In modern usage:Identification of a disease by investigation of its signs and symptoms Medical terminology:Clinical

16、 diagnosis Laboratory diagnosisX-ray diagnosis Electrocardiographic diagnosisGene diagnosisIdentification:Inquiry Physical examination Laboratory tests/Special examination Analysis:Basic knowledge of medicineOverall analysisScientific way of clinical thinking Importance of DiagnosticsEssential Bridg

17、e Tools Basic coursesClinical medicineContent of Clinical DiagnosticsSymptomatic diagnosis(症状诊断)Physical diagnosis(检体诊断)Laboratory tests or clinical ancillary testsMedical recordDiagnostic processes and the way of clinical thinkingHistory taking（病史采集)-Interview(问诊）Symptoms(症状）-patients complaints(主诉

18、)Symptomatic Diagnosis(症状诊断)Symptomatic DiagnosisSymptomatic DiagnosisSubjective sensation that patient describesFever Cough Rash Mass Physiological&functional Pathological&morphological Symptom（症状）Physical DiagnosisAbnormality observed by the physicianSign（体征）Physical examination（体格检查）Inspection(望）

19、Palpation（触）Percussion（叩）Auscultation（听）Conducted with thoroughness,alertness to detect even slight derivations from normalLaboratory test or ancillary tests Serum,Urine,Stool tests X-ray film EKG Endoscopy Ultrasonic imaging CT MRI PET(Positron Emission Tomography)Medical recordMedical record is a

20、systematized way of storing the required data,information and other relevant documentsSpecific requirement in terms of format and contentSpecial terms in clinical diagnosisImpression(初步印象）Tentative diagnosis（可能性诊断）Differential diagnosis（鉴别诊断）Evidence based medicine（循证医学）Differential diagnosis Prelim

21、inary diagnosis/Tentative diagnosis 初步诊断 可能性诊断 Exclusion of other diseases(排除其它疾病)Selecting a number of possibilities to explain the clinical and laboratory findings in the case in question The way of exclusion is called Differential diagnosisEvidence based medicineIt is the conscientious（谨慎的）,expli

22、cit（明确的）and judicious（有见解的）use of current best evidence in making decisions about the care of the individual patient It means integrating individual clinical expertise（临床专长）with the best available external clinical evidence from systematic researchEvidence based medicineOne need to:Be conscientious:

23、it requires effort and thought.Be explicit:decisions will need to be backed up by good evidence Relate to specific problems:it is not about a hypothetical average case.Integrate individual clinical experience:it does not denigrate clinical skills in history taking,examination and diagnosis.Look for

24、current best evidence:the perfect study may not yet have been published,written up or even commenced.We may have to settle for something less rigorous,but be on the look out for new research that will supersede older studies.Important aspects-interrogation To get the history in detail of a patients

25、illness The history is taken at initial contact between physician and patient As some crucial points might be overlooked by the patients,one will ask many searching questions to make the history more informative and complete,who must at the same time avoid suggesting answers Occasionally to interrog

26、ate his family memberOther important aspects The diagnostic process is very complex The number of facts that can be collected in a detailed medical history and in thorough physical examination are almost without limit The laboratory tests or specialized technical procedures that can employed are num

27、erous and costly Other important aspects Questions for interrogation,maneuver in P.E.,laboratory test should be thoughtfully selected with the view to eliminate some of the possible diagnosis and guide the search expeditiously to a specific disease Method of approaching a diagnosis:Analysis of sympt

28、oms(症状分析)Recognition of the syndrome(综合症识别)Consideration of disease mechanisms(考虑疾病机制)Important aspects Modern&advanced ancillary techniques:have their limitations.It cant reduced the importance of certain parts of the classic P.E It should be avoided to neglect fundamental methodsInterrogationPhysi

29、cal examinationScientific clinical thinkingApproachesBasic knowledge learning（基础知识的学习）Clinical practice（临床实践）Bedside activityStandardized patient床边实践标准化病人Developmental History of clinical diagnostics Western Medicine:from ancient to modern Traditional Chinese Medicine Contribution of ancient doctors

30、-WesternHippocratesBorn on the island of Cos,Greece(c.460-377 BC)The Father of medicine Hippocratic oath 希波克拉底宣言Hippocratic corpus（文集）:a collection of 70 worksHippocratic oathContribution of ancient doctors-Western Galen His work in anatomy/physiology is notable Identified artery and vein Added grea

31、tly to knowledge of the brain,spinal cord and pulseContribution of ancient doctors-WesternAuenbruggerBorn at the village of Graz,Austria(1722)Son of an innkeeperThe working experiences helped him to find PercussionAuthor of(1761)translated as On Percussion of the chest in 1936Contribution of ancient

32、 doctors-WesternLaennec RTHA French physicianInvented Auscultation and stethoscopeContribution of ancient doctors-WesternLaennec RTH1816Contribution of Western Physician17th19th centuryLeenwenhock Microscopy(end of 17th century)Fahrenheit Thermometer(1724)(体温计)Ludwig Hematomanometer(1847)(血压计)Welche

33、r Hematinometer(1854)(血细胞计数仪)20th centuryX-ray film EKG Endoscopy CT PETUltrasonic imagingCT imagingMRIPETTraditional Chinese MedicineWood FireEarthMetalWaterContribution of ancient doctors-Chinese Inspection Interrogation Smell Pulse palpation 内经内经Pay attention to:Good medical ethics Attach importa

34、nce to clinical practice Unit theory with practiceGoals Inquiry:Independent systemic inquiry Comprehensive understanding of patients chief complains,signs,symptoms and their interrelation Physical Examination:Systemic/thorough Familiar with routine tests,EKG manipulation and figure analysis Good case writing and propose the primary diagnosis Scientific clinical thinking