2022年执业药师考试部分知识点整理3 .pdf
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1、20XX年执业药师考试(主要动物药化学成分)部分知识点整理一、含胆汁酸类成分的常用动物药大纲要求:(1)胆汁酸类成分的化学结构特点(2)牛黄和熊胆中主要化学成分的结构类型(一)结构特点名称A/B B/C C/D C17取代基胆汁酸顺、反反反戊酸A/B 环为顺式稠合时为正系胆酸A/B 环为反式稠合则为别系别胆酸胆汁酸其它要点:胆烷酸(24个 C原子)、粪甾烷酸(27 或 28 个 C原子);去氧胆酸(松弛平滑肌)、鹅去氧胆酸(溶解胆结石);猪去氧胆酸(降低血液胆固醇);熊去氧胆酸(解痉、溶解胆结石)。配伍选择题A.胆酸B.别胆酸C.牛磺酸D.粪甾烷酸E.绿原酸1.属正系胆烷酸的是【正确答案】A
2、2.属别系胆烷酸的是【正确答案】B 3.有 27 个碳原子的胆烷酸是【正确答案】D(二)胆汁酸显色反应试剂阳 性 反 应现象备注Gregory Pascoe 反应45%硫酸,0.3%糠醛溶 液 显 蓝色用 于 胆 酸 含量测定Hammarsten 反应20%铬酸溶液(用乙酸配制)胆 酸 显 紫色鹅 去 氧 胆 酸不显色试剂阳 性 反 应现象备注Pettenkofer反应10%蔗糖,浓硫酸两 液 界 面出 现 紫 色环所有胆汁酸均呈现阳性反应改良乙酸,浓盐酸胆 酸 显 紫去氧胆酸、鹅文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7
3、O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9
4、U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6
5、P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8
6、D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X
7、4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编
8、码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M
9、1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7Hammarster反应色去氧胆酸不显色配伍选择题A.Keller-Kiliani反应B.呫吨氢醇反应C.Kedde反应D.Hammarsten反应E.Gregory Pascoe 反应1.可用于胆酸含量测定的是()【正确答案】E 2.胆酸显紫色,鹅去氧胆酸不显色的是()【正确答案
10、】D(三)含胆汁酸类成分的常用中药中药主要成分药典质控成分牛黄含 8%胆汁酸,主要成分为胆酸、去氧胆酸和石胆酸胆酸和胆红素熊胆胆汁酸类的碱金属盐及胆甾醇和胆红素;从生物活性方面讲,其主要有效成分为牛磺熊去氧胆酸,鹅去氧胆酸、胆酸和去氧文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7
11、O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9
12、U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6
13、P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8
14、D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X
15、4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编
16、码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M
17、1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7胆酸配伍选择题A.牛黄B.熊胆C.麝香D.人参E.蟾蜍1.含 8%胆汁酸的是【正确答案】A 2.主要成分为牛磺熊去氧胆酸的是【正确答案】B 3.主要成分具有强心作用的中药是【正确答案】E 二、含强心苷元成分的常用动物药蟾酥化学成分:蟾蜍甾二烯类(乙型)、强心甾烯蟾毒类(甲型);吲哚碱类、甾醇类以及肾上腺素、多糖、蛋白质、氨基酸和有机酸等,前两类成分具有强心作用。中国药典 以华蟾酥毒基和脂蟾毒配基为指标成分进行含量测文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O
18、9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U
19、9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P
20、8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D
21、8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4
22、Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码
23、:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1
24、H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7定,要求两者总量不得少于6.0%。生理活性:脂蟾毒配基兼有兴奋呼吸、强心和升高动脉血压等多种药理作用,已用于临床,商品名为蟾立苏。三、含其他成分的常用动物药中药主要成分生物活性麝香麝香酮(L-3-甲基十五环酮)具有特有的香气,对冠心病有与硝酸甘油同样的疗效,而且副作用小。斑蝥斑蝥素(
25、单萜)具有抗癌作用,包括抗肺癌作用、抗肝癌作用、抗卵巢癌作用、抗胰腺癌作用、抗宫颈癌作用等。水蛭水蛭素具有抗凝血作用配伍选择题A.石胆酸B.强心苷元C.5-羟色胺D.L-3-甲基十五环酮E.绿原酸1.牛黄主要化学成分是文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9L5X6P8 ZD8D8K10X4Y7文档编码:CV1M1H10Z7O9 HM9U9
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