软骨和骨--组织学和胚胎学资料.ppt

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1、软骨和骨-组织学和胚胎学1)structureofcartilagetissue-cell:chondrocyte-cartilagematrixchondrocyte:-Structure:LMembeddedincartilagelacunaperipheralcells:-smallandimmature-singleandflattenedcentralcell:-largeandmature,-roundandingroupof2-8cells-smallandroundnucleus-basophiliccytoplasm-EM:richinRERandGolgicomplex*i

2、sogenousgroup:severalcellslocatesinonelacuna,whicharederivedfromasingle(same)parentcellCartilagematrix-groundsubstance:proteoglycan:-sametolooseCT-therearemorechondroitinsulfatedistributedattheperipheryofcartilagelacuna-calledascartilagecapsule(basophilic)water-fiber:typeand number offiber depends o

3、nthetypeofcartilage2)Classification:accordingtothefibera.Hyalinecartilage:lesscollagenousfibrilarticularsurface,ribcartilage,tracheaandbronchib.Fibrouscartilage:largeamountofcollagenousfiberbundlescellsaresmallandlessintervertebraldisc,symphysispubisc.Elasticcartilage:largeamountofelasticfiberextern

4、alear,epiglottis3)perichondriumtwolayers:-outlayer:containmorefiber-protection-innerlayer:morecells-osteoprogenitorcell(fusiforminshape)4)growthofcartilage-interstitialgrowth:innerchondrocyteproliferationproducefiberandmatrix.immaturecartilage-appositionalgrowth:osteoprogenitor cellchondroblast chon

5、drocyte produce fiber andmatrix.growingandmaturecartilage2.Bone-consists of bone tissue,periosteumandendosteum,bonemarrow1)BonetissueCells:a.osteoprogenitorcell:stemcell-structure:fusiform,smallovoidnucleusslightbasophiliccytoplasmexistinperiosteumandendosteum-function:differentiated into osteoblast

6、andchondrocyteb.osteoblast:-structure:LM:singlelayerofcuboidalorlowcolumnarcellroundnucleusbasophiliccytoplasmlocatedonthesurfaceofbonetissueEM:fineprocessesrichinRER,Golgicomplex-function:.synthesize bone collagen fiber andgroundsubstance-osteoid.releasematrixvesicle:0.1umindiametermembrane-coatedf

7、unction:promotecalcificationc.osteocyte-structure:flattenedcellwithmultiplelongthinprocesseslocatedinbonelacunaandbonecanaliculusbasophiliccytoplasmadjacentcellsconnectinbonecanaliculusbygapjunctions-function:Maintainbonematrixd.osteoclast-structure:LM:multinuclearlargecell,30-100um6-50nucleiacidoph

8、iliccytoplasmlocatedatperipheralpartofboneEM:ruffledborder-processeslightzone:-undertheruffledborder-microfilamentprimarylysosome,pinosomeandsecondarylysosomeRER,mito.andGolgi-function:dissolveandabsorbbonematrixBonematrix-organicmatter:bone collagen fiber-collagenous fiber(typeIcollagen)groundsubst

9、ance:glycosaminoglycan-inorganic matter:bonesaltsHydroxyapatitecrystal:Ca10(PO4)6(OH)2pin-shapedlongitudinalarranged*bonelamella:bonematrixarranged in layers atdifferentdirection2)ArchitactureoflongboneLongboneisanorgan,madeupofbonetissue(shaftandepiphyses),periosteumandendosteum,bonemarrowshaft:con

10、sistsofcompactbonea.circumferentiallamella:/outerconcentrically-arranged/inneraroundinnersurfaceofboneb.Haversiansystem(osteon):/cylindricstructure,3-5mm/centralcanal:N,BV,CT/Haversianlamella:4-20layersc.interstitiallamella:/irregularlamella/remnantofHaversianorcircumferentiallamella*perforatingcana

11、l:/transversecanal/connectwithHaversiancanalepiphyses:composedofspongybone-trabeculae:formedbyparallelly-arrangedlamellaformaspongy-likednetwork-Bonemarrow:hemopoietictissueperiosteumandendosteum:CTmembrane-periosteum:DCTouterlayer:morefiberbundlesformperforatingfiberinnerlayer:richinBV,Nandosteoprogenitorcells-endosteum:thin,a layer of osteoprogenitorcellandCT-function:provide nutrition and osteoblast forbonegrowthandrepairing3)osteogenesisSelfstudy!此课件下载可自行编辑修改，仅供参考！此课件下载可自行编辑修改，仅供参考！感谢您的支持，我们努力做得更好！谢谢感谢您的支持，我们努力做得更好！谢谢