致病性细菌无芽胞厌氧菌医学教学课件.pptx

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1、Department of Microbiology,Harbin Medical UniversityDepartment of Microbiology,Harbin Medical University第二篇 致病性细菌第20章无芽胞厌氧菌Non-spore-forming Anaerobes Department of Microbiology,Harbin Medical University教学大纲n n了解内容uu无芽胞厌氧菌的致病性无芽胞厌氧菌的致病性Department of Microbiology,Harbin Medical University问题n n无芽胞厌氧菌的

2、致病条件及感染特点？n n与人类疾病相关的无芽胞厌氧菌有哪些？Department of Microbiology,Harbin Medical University无芽胞厌氧菌n nG+和G-的球菌、杆菌n n专性厌氧，无芽胞 n n条件致病菌Department of Microbiology,Harbin Medical University拟杆菌属 Bacteroidesn nG-G-杆菌，多形性杆菌，多形性n n厌氧培养厌氧培养n n在在20%20%胆汁培养基中胆汁培养基中生长良好生长良好Department of Microbiology,Harbin Medical Univer

3、sityDepartment of Microbiology,Harbin Medical University脆弱拟杆菌Bacteroides fragilisn n致病物质n n致病条件Department of Microbiology,Harbin Medical University拟杆菌感染特征n n感染部位接近粘膜表面n n分泌物为血性或黑色，有恶臭n n直接涂片可见细菌，培养无生长n n长期使用氨基糖苷类抗生素无效Department of Microbiology,Harbin Medical University微生物学检查法n n标本的采集n n分离培养与鉴定n n厌氧培

4、养n n气相色谱法Department of Microbiology,Harbin Medical University防治原则n n加强免疫力，减少诱发因素n n甲硝唑、替硝唑或其他广谱抗生素Department of Microbiology,Harbin Medical University其他无芽胞厌氧菌n n普雷沃菌属（Prevotella）n n梭杆菌属（Fusobacterum）n n乳杆菌属（Lactobacillus）n n双歧杆菌属（Bifidobacterium）n n丙酸杆菌属（Propionibacterium）n n厌氧球菌Department of Microbiology,Harbin Medical University小结n n无芽胞厌氧菌的致病特点及分类