最新心脏介入治疗并发症PPT课件.ppt
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1、心脏介入治疗并发症心脏介入治疗并发症Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention影响并发症发生的因素影响并发症发生的因素年龄年龄患者的健康状况患者的健康状况使用的设备和器材使用的设备和器材选择的手术方式选择的手术方式医生和其他人员的技术水平医生和其他人员的技术水平术后护理的质量术后护理的质
2、量Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionComplications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular Interventio
3、nCardiovascular InterventionCardiovascular InterventionComplications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionComplications of CatheterizationComplications of CatheterizationComp
4、lications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionComplications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionComplications
5、of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionComplications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular
6、 InterventionCardiovascular Intervention术者的因素术者的因素决策与判断错误决策与判断错误器械选择不当器械选择不当操作粗暴操作粗暴Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionACC/AHA指南指南:心脏介入并发症分类心脏介入并发症分类死亡死亡死亡死亡
7、(0.5-1.4%)(0.5-1.4%)心肌梗死心肌梗死心肌梗死心肌梗死 (1-3%)(1-3%)CABG(CABG(包括择期包括择期包括择期包括择期/急诊急诊急诊急诊/紧急紧急紧急紧急)(0.2-3%)(0.2-3%)脑卒中脑卒中脑卒中脑卒中 (0.5%)(0.5%)血管穿刺部位并发症血管穿刺部位并发症血管穿刺部位并发症血管穿刺部位并发症 (1-3%)(1-3%)(出血、闭塞、夹层、假性动脉瘤、动静脉漏出血、闭塞、夹层、假性动脉瘤、动静脉漏出血、闭塞、夹层、假性动脉瘤、动静脉漏出血、闭塞、夹层、假性动脉瘤、动静脉漏)造影剂肾病造影剂肾病造影剂肾病造影剂肾病ACC/AHA PCIACC/AHA
8、 PCIACC/AHA PCI指南指南指南指南指南指南200120012001Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionPCI时增加死亡风险的因素时增加死亡风险的因素高龄高龄女性患者女性患者糖尿病糖尿病既往心肌梗死既往心肌梗死左心功能不全或肾功能不全左心功能不全或肾功能不全左主干病变左主
9、干病变,或等同左主干病变或等同左主干病变多支血管病变多支血管病变ACC/AHA PCIACC/AHA PCIACC/AHA PCI指南指南指南指南指南指南200120012001Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention导致心肌梗死的原因导致心肌梗死的原因急性血管闭塞急性血管闭塞边支血管
10、闭塞边支血管闭塞No-reflowNo-reflow或远端血管栓塞或远端血管栓塞亚急性支架血栓亚急性支架血栓 NSTEMINSTEMI发生率约发生率约发生率约发生率约5-10%STEMI5-10%STEMI发生率约发生率约发生率约发生率约1-3%1-3%Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Interven
11、tion预防心肌梗死并发症预防心肌梗死并发症处理冠状动脉夹层处理冠状动脉夹层,防止急性闭塞防止急性闭塞保护边支血管保护边支血管,必要时置入支架必要时置入支架充分的抗血小板治疗充分的抗血小板治疗冠脉冠脉De novoDe novo病变病变,IIb/IIIaIIb/IIIa抑制剂治疗抑制剂治疗静脉桥血管病变静脉桥血管病变,远端保护装置远端保护装置Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardi
12、ovascular InterventionCardiovascular Intervention卒中并发症卒中并发症发生率发生率 0.38%19901999年间年间,9662例患者例患者,12407人次人次PCI,43例发生卒中例发生卒中高龄、左室射血分数低、糖尿病为卒中并发症高龄、左室射血分数低、糖尿病为卒中并发症 的独立预测因素的独立预测因素卒中患者预后差卒中患者预后差 院内死亡率为院内死亡率为37.2%,一年死亡率为一年死亡率为56.1%FuchsFuchs Shmuel et al.Circulation.2002;106:86-91.Shmuel et al.Circulation
13、.2002;106:86-91.Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention造影剂肾病的危险因素造影剂肾病的危险因素慢性肾功能不全慢性肾功能不全 糖尿病糖尿病高血压高血压充血性心力衰竭充血性心力衰竭高龄高龄低血容量低血容量PCIPCI相关的血流动力学不稳定相关的血流动力学不稳定大剂量的造影
14、剂大剂量的造影剂药物的相互影响药物的相互影响(阿司匹林阿司匹林,ACEI,ACEI等等)造影剂肾病造影剂肾病造影剂肾病造影剂肾病造影剂肾病造影剂肾病:Cr:Cr:Cr水平较术前升高水平较术前升高水平较术前升高水平较术前升高水平较术前升高水平较术前升高25%25%25%或绝对值增加或绝对值增加或绝对值增加或绝对值增加或绝对值增加或绝对值增加0.5mg/dl0.5mg/dl0.5mg/dl90%90%的造影剂肾病出现的造影剂肾病出现的造影剂肾病出现的造影剂肾病出现于慢性肾功能不全患者于慢性肾功能不全患者于慢性肾功能不全患者于慢性肾功能不全患者Complications of Catheteriza
15、tionComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention预防造影剂肾病的药物预防造影剂肾病的药物静脉注射含盐溶液静脉注射含盐溶液静脉注射含盐溶液静脉注射含盐溶液-水化治疗水化治疗水化治疗水化治疗 静脉注射优于口服静脉注射优于口服静脉注射优于口服静脉注射优于口服 等渗优于低渗等渗优于低渗等渗优于低渗等渗优于低渗 碳酸氢钠碳酸氢钠碳酸氢钠碳酸氢钠 术前术前术前
16、术前6-126-12小时小时小时小时1ml/kg1ml/kg至术后至术后至术后至术后12-2412-24小时小时小时小时,根据心功能情况调整根据心功能情况调整根据心功能情况调整根据心功能情况调整,必要时利尿剂必要时利尿剂必要时利尿剂必要时利尿剂低渗或等渗造影剂低渗或等渗造影剂低渗或等渗造影剂低渗或等渗造影剂NN乙酰半胱氨酸乙酰半胱氨酸乙酰半胱氨酸乙酰半胱氨酸?呋塞米呋塞米呋塞米呋塞米,ANP,ANP,钙通道阻滞剂等钙通道阻滞剂等钙通道阻滞剂等钙通道阻滞剂等Am J Roentgenol Am J Roentgenol Am J Roentgenol 2004;2004;2004;183(6):
17、1673-1689.183(6):1673-1689.183(6):1673-1689.Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention 冠状动脉相关并发症冠状动脉相关并发症急性血管闭塞急性血管闭塞血管夹层血管夹层冠状动脉穿孔冠状动脉穿孔血管痉挛血管痉挛Slow-Flow与与No-Reflow
18、气体栓塞气体栓塞Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention急性血管闭塞急性血管闭塞Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiov
19、ascular InterventionCardiovascular InterventionCardiovascular Intervention急性血管闭塞急性血管闭塞:发生率发生率2%急性血管闭塞的临床因素急性血管闭塞的临床因素:心源性休克心源性休克 多支病变多支病变 高龄高龄 充血性心力衰竭充血性心力衰竭 肾功能不全肾功能不全 女性女性 糖尿病糖尿病 不稳定心绞痛不稳定心绞痛 急性心肌梗死急性心肌梗死Complications of CatheterizationComplications of CatheterizationComplications of Catheterizati
20、onCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention急性血管闭塞的病变因素急性血管闭塞的病变因素:含血栓病变含血栓病变 老化静脉桥老化静脉桥 分叉病变分叉病变 成角病变成角病变 病变远端迂曲病变远端迂曲 长病变长病变Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascul
21、ar InterventionCardiovascular Intervention急性血管闭塞常见原因急性血管闭塞常见原因血管夹层血管夹层 绝大多数为介入器械损伤所致绝大多数为介入器械损伤所致处理含血栓病变处理含血栓病变冠状动脉痉挛冠状动脉痉挛 但通常不是引起闭塞的直接原因但通常不是引起闭塞的直接原因Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular Interventi
22、onCardiovascular Intervention急性闭塞后患者死亡的决定因素急性闭塞后患者死亡的决定因素是否存在足够的侧支血管是否存在足够的侧支血管是否存在多支病变是否存在多支病变是否存在心功能低下是否存在心功能低下Jeopardy积分显示大片心肌处于危险之中积分显示大片心肌处于危险之中恢复冠脉前向血流所需的时间恢复冠脉前向血流所需的时间Catheter Cardiovasc Interv 2005Catheter Cardiovasc Interv 2005;64:395401.64:395401.Complications of CatheterizationComplicati
23、ons of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular InterventionJeopardy积分积分积分越高积分越高积分越高积分越高,血管闭塞后死亡风险越大血管闭塞后死亡风险越大血管闭塞后死亡风险越大血管闭塞后死亡风险越大!Ellis SG et al.Am J Cardiol 1991;68:1447-1451.Ellis SG et al.Am J Cardiol 1991;68:1447-1451
24、.Complications of CatheterizationComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention急性血管闭塞的临床症状急性血管闭塞的临床症状胸痛胸痛心电图变化心电图变化 ST段抬高或压低段抬高或压低低血压低血压心律失常心律失常 传导阻滞或室颤导致心性猝死传导阻滞或室颤导致心性猝死Complications of Catheterizati
25、onComplications of CatheterizationComplications of CatheterizationCardiovascular InterventionCardiovascular InterventionCardiovascular Intervention急性闭塞急性闭塞冠脉内注射硝酸甘油冠脉内注射硝酸甘油冠脉内注射硝酸甘油冠脉内注射硝酸甘油100-200mcg100-200mcg100-200mcg100-200mcg重复重复重复重复PTCA(PTCA(球囊球囊球囊球囊/动脉动脉动脉动脉=1.0-1.1)=1.0-1.1)再次造影再次造影再次造影再次造影
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