T组合使用课件.ppt
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1、1BWBubble CPAP2BW哥伦比亚哥伦比亚 CPAP(Bubble CPAP)3BWBubble CPAP的作用的作用Bubble CPAP 显著地减少了低出生体重婴儿发生慢性肺疾病的事故。Bubble CPAP通过改善气体交换,可以降低潮气量和呼吸频率,降低呼吸功,减少呼吸疲劳和对气管插管的需要。Ref:Mary Ellen Avery,MD,William Tooley,MD,et.al.(Jan 1987).Is Chronic Lung Disease in Low Birth Weight Infants Preventable?A Survey of Eight Cente
2、rs.Pediatrics 79(1):26-30 Kyong-Soon Lee,Michael Dunn,et.al.(1998)A comparison of Underwater Bubble Continuous Positive Airway Pressure with Ventilator-Derived Continuous Positive Airway Pressure in Premature Neonates Ready for Extubation.Biol Neonate 73:69-754BWBubble CPAP的作用的作用Ref:J Paediatr Child
3、 Health.2001 Apr;37(2):161-7.5BWBubble CPAP的作用的作用Early bubble CPAP reduced delivery room intubations,days on mechanical ventilation,postnatal steroid use and was associated with increased postnatal weight gain with no increased complications.Ref:Narendran V,Donovan EF,Hoath SB,et.al.Early bubble CPA
4、P and outcomes in ELBW preterm infants.J Perinatol.2003 Apr-May;23(3):195-9.6BWBubble CPAP的作用的作用CONCLUSIONS:Compared to constant pressure technique,bubble continuous positive airway pressure promotes enhanced airway patency during treatment of acute postnatal respiratory disease in preterm lambs and
5、 may offer protection against lung injury.Ref:Pillow JJ,Hillman N,Moss TJ,et.al.Am J Respir Crit Care Med.2007 Apr 12 7BWBubble CPAP的作用的作用CONCLUSIONS:Bubble CPAP is as effective as IFD CPAP in the post-extubation management of infants with RDS;however,in infants ventilated for or=14 days,bubble CPAP
6、 is associated with a significantly higher rate of successful extubation.Bubble CPAP also is associated with a significantly reduced duration of CPAP support.Ref:Gupta S,Sinha SK,Tin W,Donn SM.J Pediatr.2009 May;154(5):633-4.8BW压力波形压力波形(体内体内)振荡压力波形的确从气道传递到肺,而且低顺应性的压力波形所含有的高频成分和能量可能对婴儿的气体氧合有所帮助。Ref:T
7、ravadi JN and Pillow JJ.Effect of Compliance and Flow on Pressure Waveform in the Lung During Bubble CPAP.King Edward Memorial andPrincess Margaret Hosps,and Institute for Child Health Research,Perth,An in vitro Study.Perinatal Society of Australia&New Zealand 5th Annual Congress in Conjunction with
8、 the Australasian Society 9BW压力波形压力波形 (体内)(体内)婴儿体重是婴儿体重是15001500克,克,CPAP CPAP 压力为压力为6 6厘米水柱厘米水柱10BW压力波形压力波形(体内)(体内)CPAP的压力为的压力为5 5cmcm水柱水柱11BWBubble CPAP的好处的好处结论是 bubble CPAP增加功能残气量,改善氧合、提高肺的顺应性。通过改善气体弥散降低新生儿的呼吸功。减少机械通气的不良后果。降低慢性肺疾病的发病率。12BWBubble CPAP的适应症的适应症任何明显呼吸窘迫的症状 -呼吸急促(tachypnoea),鼻翼扇动,喉音,发绀
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