医学类英语翻译.pdf

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1、医学类英语翻译 第一篇 2012 Sep 24.doi:10.1002/hed.23159.Epub ahead of print Surgical management of inverted papilloma:Approaching a new standard for surgery.手术治疗内翻性乳头瘤：接近新标准的手术 Carta F,Blancal JP,Verillaud B,Tran H,Sauvaget E,Kania R,Herman P.Source 来源 Assistance Publique-H?pitaux de Paris,Department of Ear,N

2、ose and Throat,H?pital Lariboisire,Universit Paris-Diderot,Paris,France.Abstract 摘要 BACKGROUND:背景：Inverted papilloma surgery is currently performed primarily with an endoscopic approach,a technique that has a recurrence rate of 12%.However,a recent study reported a recurrence rate of 5%with a strate

3、gy based on subperiosteal dissection of the tumor,with limited indications for using an external approach.The aim of this work was to evaluate whether different teams using the same surgical concepts could reproduce the excellent results that were recently reported.对内翻性乳头瘤的治疗目前主要采取的方法是内镜的方法，这种方法有 12

4、%的复发率。然而，最近一项研究表明以骨膜剥离肿瘤的方法为基础和有限的迹象为外部参考方式可以控制它的复发率为 5%。这项工作的目的是评估不同的团队使用同样的手术观念，是否会重现最近所报道的优异成果。METHODS:方法：This study is a retrospective chart review of 71 consecutive patients with inverted papilloma who were treated during the last 10 years.这项研究方式是对过去十年间一共 71 例内翻性乳头瘤病人的回访复查。RESULTS:In all,80%of

5、the patients were treated using a purely endoscopic approach.The mean follow-up period was 31.6 months.The recurrence rate was 3.3%for cases with at least a 12-month follow-up.结果：总之，80%的病人的治疗是使用纯粹的内镜办法。平均随访时间为 31.6 个月。复发率为 3.3%例事件至少需要 12 个月的随访时间。CONCLUSIONS:This work confirms the results described i

6、n recent literature and further supports transnasal endoscopic surgery to manage inverted papilloma.?2012 Wiley Periodicals,Inc.Head Neck,2012.结论：这项工作证实了最近的文献所描述的及进一步支持鼻内窥镜手术的治疗内翻性乳头状瘤的结论。Copyright?2012 Wiley Periodicals,Inc.PMID:23002029 PubMed-as supplied by publisher 第 2 篇 2012 Sep 19.pii:S0181-5

7、512(12)00172-6.doi:10.1016/j.jfo.2011.10.014.Epub ahead of print Evaluation of reconstructive techniques after orbital exenteration in 56 cases.对 56 例眼窝切除后重建方法的评估 Article in French Langlois B,Jacomet PV,Putterman M,Morax S,Galatoire O.Source 来源 Service de chirurgie reconstructive orbito-palpbrale,fo

8、ndation Rothschild,25-29,rue Manin,75019 Paris,France.Electronic address:lblandihttp:/ 摘要 PURPOSE:目的：To describe the management of orbital exenterations and the surgical techniques for the reconstruction of orbital exenteration cavities.为了眼窝腔的重建，对眼窝切除术和外科技术的管理的描述 PATIENTS AND METHODS:This retrospect

9、ive study includes 56 patients who underwent orbital exenteration between 2000 and 2009.Patients age at the time of exenteration,diagnoses,complications and reconstructive techniques were studied.病人与方法：本回顾性调查针对的是 56 个在 2000 年2009 年之间接受了眼窝切除术的患者。对这些患者在进行切除术时、诊断时、发症时及进行重建手术的年龄进行调查。RESULTS:Fifty-six pa

10、tients-31 male and 25 female patients-who underwent orbital exenteration between 2000 to 2009 were included in the study.The mean age was 62.5 years at the time of exenteration.Average follow-up was 23 months.The principal diagnoses were basal cell carcinoma of the eyelids(25%)and conjunctival melan

11、oma(20%).For orbital reconstruction,18 patients(32%)had a muscle flap,and 24 patients(43%)underwent secondary reconstruction by bone-anchored implants after spontaneous epithelialisation of the orbit.Approximately 50%of the patients received postoperative radiation therapy.结果：此次被调查研究的一共 56 人，这些人都是在

12、2000 年至 2009 年期间进行眼窝切除手术的，其中男性 31 人、女性 25 人。这些进行手术的人平均年龄是 62.5 岁。每个人平均调查的时间是 23 个月。主要诊断的是眼睑的基底细胞癌（25%）和结膜黑色素瘤（20%）。在这些眼窝重建当中，18 个病人（占全体的 32%）有肌皮瓣，24 个病人（43%）在自发性表皮的眼窝上进行骨锚式植入的二次重建。大约 50%的患者接受术后放射治疗。DISCUSSION:Surgical reconstruction using muscle flaps may mask recurrent tumor.Epithelialisation and b

13、one-anchored implants supporting the prosthesis allow for recurrent cancer surveillance while providing better stabilization of the prosthesis.Radiation therapy seems to render the orbit more fragile and thus less stable for implants.论述：使用肌肉瓣的眼窝重建手术可能会掩盖肿瘤复发。如果能够提供更加稳定假肢的同时，表皮和骨锚式植入支持假肢是允许用来对癌症复发进行监

14、测的。放射治疗似乎使轨道更加脆弱，因此对植入物的方式很不稳定。CONCLUSION:Orbital exenteration is a mutilating technique.Rehabilitation techniques have been improved,in particular the bone-anchored implants which allow adaptation of the prosthesis with satisfactory cosmetic results.结论：眼窝切除术是一种残害技术。康复技术已经得到改善，尤其是骨锚式植入技术，它允许美容效果较为满意

15、的假肢去适应。Copyright?2012 Elsevier Masson SAS.All rights reserved.PMID:22999254 PubMed-as supplied by publisher 第 3 片 2012 Sep 21.Epub ahead of print Immunohistochemistry in the era of personalised medicine.McCourt CM,Boyle D,James J,Salto-Tellez M.Source Molecular Pathology Programme,Centre for Cancer

16、Research and Cell Biology,Queens University Belfast,Belfast,UK.Abstract BACKGROUND:Immunohistochemistry(IHC)plays a central role in the histopathological classification of diseases,including cancer.More recently,the importance of immunohistochemical staining is increasing.IHC usage in diagnostics is

17、 invaluable;however,the genetic and therapeutic significance of biomarker immunostaining has become equally relevant.CONTENT:In this article,we would like to analyse the three distinct roles of IHC and review their individual impacts on modern diagnostic pathology:(1)diagnostic IHC;(2)genetic IHC an

18、d(3)therapeutic IHC.SUMMARY:Thus,we will characterise the different analytical processes that are required in the three approaches to IHC usage stated above,as well as the clinical significance and overall importance in patient management.This will allow us to hypothesise on the most appropriate laboratory environment and detection methods for the future.PMID:23002284 PubMed-as supplied by publisher