(2)--ARDS病理生理学课件.ppt

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1、PathophysiologySevere Acute Respiratory Syndrome(SARS)PathophysiologyMiddle East Respiratory Syndrome(MERS)Pathophysiology3Acute Respiratory Distress Syndrome(ARDS)Susanon admission:BP 80/50 milimeter of mercury(mmHg)chest radiograph:normal lungafter 24h:R 35/min(1620/min),cyanosis,PaO2 35mmHg(100mm

2、Hg),crackle chest radiogragh:fog-like infiltration in lunghistological exam:edema,hyaline membranes Case report airplane landing accident：fracture,spleen rupture,burnPathophysiologyShockRespiratory failureCase reportARDSPathophysiology6 Acute Respiratory Distress Syndrome(ARDS)is resulting from by v

3、arious factors.acute respiratory failureinjury of alveolar-capillary membraneConceptPathophysiology7What factors can damage alveolar-capilary membrane and lead to ARDS?PathophysiologyARDSInhalation ShockTraumaDrug overdoseInfectionBurnDirect injury factorsSystemic pathological processCausesPathophysiology91.肺水肿；肺水肿；2.肺内透明膜形成；肺内透明膜形成；3.肺内微血栓形成肺内微血栓形成；4.肺不张；肺不张；ARDS时肺的时肺的病理改病理改变Pathophysiology主要主要临床表床表现：1.难以控制的以控制的严重的呼吸困重的呼吸困难2.难以以纠正的、正的、顽固性的低氧血症；固性的低氧血症；3.X线呈呈现弥漫性肺泡浸弥漫性肺泡浸润；4.可累及多系可累及多系统多多脏器器Pathophysiology11THANK YOU!