职称英语-职称英语卫生类b级模拟21.pdf
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1、职称英语卫生类B级模拟21第1部分:词汇选项5、工、Helooked dismayed when he h e a rd th e new s.A.p a leB.h u r tf u lC.d o u b tfu lD.d is a p p o in te d2、I fs beyond mortal pow er to b rin g a dead man back to l i f eA.humanB.s p i r i t u a lC.m a te ria lD.e le c tr o n ic3、A llp ro p o s a ls a relik e ly to be rejec
2、ted.A.a c c e p te dB.re fu s e dC.n e g le c te dD.b e lie v e d4、Thes i s t e r s c a n11 tolerate each o th e r.A.h a teB,b e a rC.lik eD.c r i t i c i z eJ a n e1 s unusual b e h a v io r p u z z le d h e r p a r e n ts.A.abnorm alC.re p e a te dB.fr ig h te n in gD.funny6、He had to consider th
3、e o f f e r.Anyway,heA.s e t upC.c o n s tru c thad to r e a r h is w hole fa m ily.B.D.re b u ildr a is e7、He was evidently h o ld in g lig h t o n to h im se lf ab o u t so m eth in g.A.r e lu c ta n tly B.o b v io u slyC.seem in g ly D.c o n c lu s iv e ly8、They resembled each o th e r in c o lo
4、r b u t n o tA.w ere s im ila r to B.C.w ere lik e ly D.in s h a p e.d if f e r e n tia te dm o d ified9、You sh o u ld conform to th e u sag e o f s o c ie ty.A.c o n fro n t B.C ad o p t D.a c q u a in tfo llo w10 He inquired w h eth er i t was p o s s ib le to le a v e h is s u itc a s e a t th e
5、ra ilw a ys t a t i o n.A.in s is te d B.su g g e ste dC.ask ed D.c a lle d11 Subteiranean stre am s have c u t th ro u g h lim e sto n e to form m ile s o f p a ssa g e sand cav es such as K entucky*s Mammoth C ave.A.S econdary B.U ndergroundC.U nharnessed D.M in isc u le12 The m in is te r approve
6、d th e b u ild in g p la n s a f t e r he d is c u s s e d w ith o th e rm in is te r s.A.a g re ed B.opposedC.c a n c e le d D.d e lig h te d13 Tom dropped off in fr o n t o f f i r e.A.drop a tC.doze o ffB.drop awayD.ta k e o ff14、Parents should realized that example is better than precept1 1.A.in
7、struction B.educationC.imagination D.morality15 For most allergies,the best treatment is elimination of the bothersomesubstances from the sensitive person*s environment.A.unnatural B.dangerousC.irritating D.surrounding第2部分:阅读判断Souped-up(效力增强了的)enzymes that flush poisons out of cells moreefficiently
8、than their natural counterparts(对应的人或物)could alleviate someof the severe side effects of chemotherapy and so improve the chances of curingcancers.Many anticancer drugs attack tumor cells because they divide more rapidlythan heathy cells.But some vital healthy cells also divide faster thanormal zand
9、these are destroyed as well.The most vital cells caught in the chemicalcross-fire are those made in the bone marrow(骨髓).Under normal circumstances,these mature into platelets(血小板),which are vital for wound-healing,andwhite blood cells that fight infections.If levels of these cells fall,patientsbecom
10、e dangerously vulnerable to infection and can suffer such severe internalbleeding that treatment has to be stopped.Surviving cancer cells can thenre-grow and reduce the effectiveness of the therapy.Bill Fehl and his colleagues at the University of Wisconsin Medical Schoolhave engineered an enzyme th
11、at could make bone marrow cells resistant to thecancer drugs,so higher doses can be given and side effects reduced.The ideais to take healthy bone marrow cells f rompatients before they begin chemotherapy,then equip these cells with the genes that make the enzyme drug-resistant.When returned to the
12、patient,the improved bone marrow cells could then withstandheavy doses of the drugs.The natural version of the enzymecalled glutathione Stransferase胱甘肽S转移酶)is produced mainly in the liver and catalyses(催化)the breakdownof compounds that might otherwise damage DNA in cells.GST also neutralizes(中和)the
13、toxic breakdown products of anticancer drugsz which makes it suitablefor protecting bone marrow cells.But natural GST does not work efficientlyenough to avoid being swamped by high doses of drugs.GST catalyses a reaction between potentially toxic compounds andglutathionea peptide(肽)produced in almos
14、t all cells of the body.The GSTmolecule has a cavity,or active site,where the two molecules are broughtclose enough to react.This neutralizes the toxin,which passes into the bloodto be excreted in the patient*s urine.Using machines for synthesizing(结合,使合成)DNA,Fehl and his colleaguesmade thousands of
15、 scrambled versions of the parts of the GST gene that makethe active site of the enzyme.They inserted these scrambled genes intoEscherichia coll.By exposing the bacteria to increasing quantities of theanticancer drug z mechlorethamine(M ),Fehl screened out the ones most tolerantto the drug.nBy this
16、method,we made enzymes 30 times as efficient as the naturalone,”says Fehl.In other wordsz it took 30 times as much drug to kill thebacteria.Fehl has already exposed mice carrying copies of the doctored gene toknown carcinogens(致癌物)to see how efficient the gene is at mopping up thetoxins.The more eff
17、icient it is,the less damage the toxins do and fewertumors should appear.We anticipate a significant reduction(in the number of cancers)inthe group carrying the gene,says Fehl,who is still analyzing the results.Fehl*s team has applied for a patent covering the techniquez and hopes todevelop treatmen
18、ts with Systemix,a company based in Palo Alto,California.Brian Ketterer,who heads the Cancer Research Campaign1s moleculartoxicology group in London,says Fehl*s work could be important.But he warnsthat the proposed strategy would not protect cells lining the gut fromchemotherapy drugs.16、The passage
19、 mainly discusses about the toxic reaction of anticancer drugs.A.Right B.Wrong C.Not mentioned17、Dietary intervention may work even after precancerous warning signs haveappeared.A.Right B.Wrong C.Not mentioned18、Being resistant to the anticancer drugsz bone marrow cells can greatlyreduce the side ef
20、fects.A.Right B.Wrong C.Not mentioned19、Wheat bran may lower the risk of colon cancer.A.Right B.Wrong C.Not mentioned20、The enzyme engineered by Fehl1s team is superior to the natural enzymein withstanding Heavy doses of the drugs.A.Right B.Wrong C.Not mentioned21 Fehl picked up the most tolerant sc
21、rambled gene by using machines.A.Right B.Wrong C.Not mentioned22、The strategy proposed by Fehl can protect cells in various parts of thebody from chemotherapy drugs.A.Right B.Wrong C.Not mentioned第3部分:概括大意与完成句子Cancer is a disease in which cells multiply without control,destroy healthytissuez and end
22、anger life.About 100 kinds of cancer attack human beings.The disease is a leading cause of death in many countries.In the United Statesand Canada,only diseases of the heart and blood vessels kill more people.Cancer occurs in most species of animals and in many kinds of plants,as wellas in human bein
23、gs.2.Cancer strikes people of all ages but especially middle-aged personsand the elderly.It occurs about equally among people of both sexes.The diseasecan attack any part of the body and may spread to other parts.However,theparts most often affected are the skin,the digestive organs,the lungsz thema
24、le prostate,and the female breasts.3.Scientists do not know exactly why cancer develops.Most expertsagree that people develop cancer mainly through repeated or prolonged contactwithone or more cancer-causing agents,called carcinogens.These agents includethe tars in tobacco smokez a variety of other
25、chemicals,and certain kindsof radiation.In many cases,cancer can be prevented if a known agent is avoidedor eliminated.The elimination of cigarette smoking,for example,would preventmost cases of lung cancer and about a third of all cases of cancer.Scientistsalso believe that some people may inherit
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